Interactions of bacteria with non-phagocytic cells.

Interactions of bacteria with non-phagocytic cells.
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细菌与非吞噬细胞的相互作用。

DOI:
10.1016/0952-7915(94)90146-5
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发表时间:
1994
影响因子:
7
通讯作者:
Galán,JE
Galán,JE
中科院分区:
医学2区
文献类型:
--
作者:
Galán,JE

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越来越清楚的是,细菌病原体可以操纵宿主细胞,使之对自己有利。最近,我们已经了解了更多关于微生物进化来破坏正常宿主细胞功能的不同策略。这些策略使细菌能够进入宿主细胞,在宿主细胞内生存和复制,并传播到邻近细胞,而不需要细胞外阶段。在接下来的几年里,我们期望对这些机制有更多的了解,在这个过程中,我们很可能会对宿主本身有更多的了解。
It is becoming increasingly clear that bacterial pathogens can manipulate the host cell to their advantage. Recently, we have learnt more about the different strategies that microorganisms have evolved to subvert normal host-cellular functions. These strategies allow bacteria to gain access to, survive, and replicate within host cells, as well as to spread to neighboring cells, without the need for an extracellular phase. During the next few years, we expect to learn much more about these mechanisms and, in the process, it is likely that we will learn more about the host itself.
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