The Role of Age, Gender, Education, and Intelligence in P50, N100, and P200 Auditory Sensory Gating.
The Role of Age, Gender, Education, and Intelligence in P50, N100, and P200 Auditory Sensory Gating.
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DOI：
10.1027/0269-8803.23.2.52
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发表时间：
2009
影响因子：
1.3
通讯作者：
Swann, Alan C.
中科院分区：
文献类型：
--
作者：
Lijffijt, Marijn;Moeller, F. Gerard;Boutros, Nash N.;Burroughs, Scott;Lane, Scott D.;Steinberg, Joel L.;Swann, Alan C.
P50、N100和P200听觉感觉门控反映了保护高阶功能完整性的不同机制。他们与多种精神疾病有关。最近的研究表明，年龄和性别对控制对象的感觉门控的影响（有限），这表明可能有其他来源的差异。两个潜在的来源可能是教育和智力（智力能力），这些变量在不同的研究和不同的实验组中经常不同。我们探讨了年龄，性别，教育和智力（Shipley智力量表）的P50，N100和P200感觉门控测量配对点击范例在60名健康受试者招募的潜在影响，从一般人群。增加的智力能力与更强的N100和P200门控和更明显的N100和P200振幅有关。此外，年龄增加与P200门控较弱和P200振幅较小有关。性别的影响可以忽略不计。智力能力或年龄可能导致N100或P200听觉感觉门控的变化，在临床和对照组研究感觉门控时应加以控制。
P50, N100, and P200 auditory sensory gating reflect distinct mechanisms involved in protecting the integrity of higher-order functions. They have been implicated in multiple psychiatric disorders. Recent studies showed the (limited) effects of age and gender on sensory gating in control subjects, suggesting there may be other sources of variance. Two potential sources may be education and intelligence (intellectual capability), variables that frequently differ across studies and across experimental groups. We explored potential effects of age, gender, education, and intelligence (Shipley intelligence scale) on P50, N100, and P200 sensory gating measured with the paired-click paradigm in 60 healthy subjects recruited from the general population. Increased intellectual capability related to stronger N100 and P200 gating and more pronounced N100 and P200 amplitudes. In addition, increased age related to weaker P200 gating and smaller P200 amplitudes. Gender had negligible effects. Intellectual capability or age could contribute to variation in N100 or P200 auditory sensory gating and should be controlled for when studying sensory gating in clinical and control groups.
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影响因子：
10.6
作者：
JERGER, K;BIGGINS, C;FEIN, G
通讯作者：
FEIN, G
DOI：
10.1016/0013-4694(70)90183-5
发表时间：
1970-01-01
期刊：
ELECTROENCEPHALOGRAPHY AND CLINICAL NEUROPHYSIOLOGY
影响因子：
--
作者：
FRUHSTOR.H;SOVERI, P;JARVILEH.T
通讯作者：
JARVILEH.T
影响因子：
4.8
作者：
Ghisolfi, Eduardo S.;Heldt, Elizeth;Lara, Diogo R.
通讯作者：
Lara, Diogo R.
影响因子：
11.3
作者：
Boutros, NN;Korzyukov, O;Bell, M
通讯作者：
Bell, M
影响因子：
3.7
作者：
Kisley, MA;Noecker, TL;Guinther, PM
通讯作者：
Guinther, PM