Research diagnostic criteria for mild cognitive impairment with Lewy bodies: A systematic review and meta-analysis.
Research diagnostic criteria for mild cognitive impairment with Lewy bodies: A systematic review and meta-analysis.
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DOI：
10.1002/alz.13105
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发表时间：
2023-07
影响因子：
14
通讯作者：
Bonanni, Laura
中科院分区：
文献类型：
--
作者：
Donaghy, Paul C.;Carrarini, Claudia;Ferreira, Daniel;Habich, Annegret;Aarsland, Dag;Babiloni, Claudio;Bayram, Ece;Kane, Joseph P. M.;Lewis, Simon J. G.;Pilotto, Andrea;Thomas, Alan J.;Bonanni, Laura
关键词：
轻度认知功能障碍伴路易体（MCI-LB）的可操作化研究标准于2020年发布。本系统性综述和荟萃分析的目的是审查标准中规定的MCI-LB诊断临床特征和生物标志物的证据。于2022年9月28日检索MEDLINE、PubMed和Embase以查找相关文章。如果文章提供了报告MCI-LB诊断特征发生率的原始数据，则将其纳入。共纳入57篇文章。荟萃分析支持将当前临床特征纳入诊断标准。纹状体多巴胺能成像和间碘苄胍心脏造影的证据虽然有限，但支持将其纳入。定量脑电图（EEG）和氟脱氧葡萄糖正电子发射断层扫描（PET）显示出作为诊断生物标志物的前景。现有证据在很大程度上支持MCI-LB的当前诊断标准。进一步的证据将有助于完善诊断标准，并了解如何最好地将其应用于临床实践和研究。
Operationalized research criteria for mild cognitive impairment with Lewy bodies (MCI-LB) were published in 2020. The aim of this systematic review and meta-analysis was to review the evidence for the diagnostic clinical features and biomarkers in MCI-LB set out in the criteria. MEDLINE, PubMed, and Embase were searched on 9/28/22 for relevant articles. Articles were included if they presented original data reporting the rates of diagnostic features in MCI-LB. Fifty-seven articles were included. The meta-analysis supported the inclusion of the current clinical features in the diagnostic criteria. Evidence for striatal dopaminergic imaging and meta-iodobenzylguanidine cardiac scintigraphy, though limited, supports their inclusion. Quantitative electroencephalogram (EEG) and fluorodeoxyglucose positron emission tomography (PET) show promise as diagnostic biomarkers. The available evidence largely supports the current diagnostic criteria for MCI-LB. Further evidence will help refine the diagnostic criteria and understand how best to apply them in clinical practice and research.
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影响因子：
3.7
作者：
Blanc F;Colloby SJ;Philippi N;de Pétigny X;Jung B;Demuynck C;Phillipps C;Anthony P;Thomas A;Bing F;Lamy J;Martin-Hunyadi C;O'Brien JT;Cretin B;McKeith I;Armspach JP;Taylor JP
通讯作者：
Taylor JP
影响因子：
4
作者：
Hamilton, Calum A.;Frith, James;Donaghy, Paul C.;Barker, Sally A. H.;Durcan, Rory;Lawley, Sarah;Barnett, Nicola;Firbank, Michael;Roberts, Gemma;Taylor, John-Paul;Allan, Louise M.;O'Brien, John;Yarnall, Alison J.;Thomas, Alan J.
通讯作者：
Thomas, Alan J.
影响因子：
11
作者：
Bousiges, Olivier;Bombois, Stephanie;Blanc, Frederic
通讯作者：
Blanc, Frederic
DOI：
10.1186/s13195-016-0198-6
发表时间：
2016-07-20
期刊：
Alzheimer's research & therapy
影响因子：
--
作者：
Blanc F;Colloby SJ;Cretin B;de Sousa PL;Demuynck C;O'Brien JT;Martin-Hunyadi C;McKeith I;Philippi N;Taylor JP
通讯作者：
Taylor JP
影响因子：
8.6
作者：
Bayram, Ece;Coughlin, David G.;Litvan, Irene
通讯作者：
Litvan, Irene