Resistance training improves body composition and increases matrix metalloproteinase 2 activity in biceps and gastrocnemius muscles of diet-induced obese rats.
Resistance training improves body composition and increases matrix metalloproteinase 2 activity in biceps and gastrocnemius muscles of diet-induced obese rats.
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DOI：
10.6061/clinics/2014(04)08
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发表时间：
2014
期刊：
影响因子：
--
通讯作者：
Kraemer-Aguiar LG
中科院分区：
文献类型：
--
作者：
Souza MV;Leite RD;Souza Lino AD;Marqueti Rde C;Bernardes CF;Araújo HS;Bouskela E;Shiguemoto GE;Andrade Perez SE;Kraemer-Aguiar LG
我们研究了抗阻训练对高脂饮食大鼠身体组成和骨骼肌基质金属蛋白酶2活性的影响。将32只Wistar大鼠按饮食和运动状态分为4组（n = 8/每组）：对照组（标准饮食）、肥胖对照组（高脂饮食）、抗阻训练组（标准饮食）和肥胖抗阻训练组（高脂饮食）。 动物喂食高脂肪饮食12周，以促进体重过度增加。阻力训练组进行12周的训练期后，这一时期的垂直阶梯，每周三次。采用双能X线吸收法测定脂肪百分比、去脂质量和脂肪质量，采用酶谱法分析肱二头肌和腓肠肌中基质金属蛋白酶2的活性。阻力训练显著降低了两组的体重、脂肪量和脂肪百分比（p<0.05）。最大负重训练组与对照组无显著性差异，但相对力量训练组高于对照组（P<0.05）。值得注意的是，在两个训练组的测试肌肉中注意到基质金属蛋白酶2活性增加（p<0.05）。总之，改变身体组成和肌肉基质金属蛋白酶2活性促进过度增重积极修改阻力训练。
We investigated the influence of resistance training on body composition and matrix metalloproteinase 2 activity in skeletal muscles of rats fed a high-fat diet. Thirty-two Wistar rats were divided into four experimental groups (n = 8/each) according to diet and exercise status: Control (standard diet), Obese Control (high-fat diet), Resistance Training (standard diet) and Obese Resistance Training (high-fat diet) groups. Animals were fed a high-fat diet for 12 weeks to promote excessive weight gain. Resistance Training groups performed 12 weeks of training periods after this period in a vertical ladder three times/week. Fat percentage, fat-free mass and fat mass were assessed using dual-energy X-ray absorptiometry, and matrix metalloproteinase 2 activity in biceps and gastrocnemius muscles was analyzed using zymography. Resistance training significantly reduced body and fat masses and fat percentages in both trained groups (p<0.05). The maximal carrying load between trained groups was not different, but relative force was higher in the Resistance Training group (p<0.05). Of note, increased matrix metalloproteinase 2 activity was noted in the tested muscles of both trained groups (p<0.05). In conclusion, altered body composition and muscle matrix metalloproteinase 2 activity promoted by excessive weight gain were positively modified by resistance training.
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影响因子：
4.8
作者：
Marqueti, Rita C.;Parizotto, Nivaldo A.;Selistre-de-Araujo, Heloisa S.
通讯作者：
Selistre-de-Araujo, Heloisa S.
影响因子：
6.3
作者：
Kurosaka, M.;Naito, H.;Katamoto, S.
通讯作者：
Katamoto, S.
影响因子：
2.4
作者：
Kjær, M;Magnusson, P;Langberg, H
通讯作者：
Langberg, H
影响因子：
2.7
作者：
Speretta, Guilherme Fleury Fina;Rosante, Marisa Cristina;Duarte, Ana Claudia Garcia de Oliveira
通讯作者：
Duarte, Ana Claudia Garcia de Oliveira
影响因子：
2.6
作者：
Malatesta, Manuela;Fattoretti, Patrizia;Zancanaro, Carlo
通讯作者：
Zancanaro, Carlo