The association of unconventional natural gas development with diagnosis and treatment of internalizing disorders among adolescents in Pennsylvania using electronic health records.
The association of unconventional natural gas development with diagnosis and treatment of internalizing disorders among adolescents in Pennsylvania using electronic health records.
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DOI：
10.1016/j.envres.2022.113167
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发表时间：
2022-09
影响因子：
8.3
通讯作者：
Schwartz, Brian S.
中科院分区：
文献类型：
--
作者：
Gorski-Steiner, Irena;Bandeen-Roche, Karen;Volk, Heather E.;O'Dell, Sean;Schwartz, Brian S.
非常规天然气开发（UNGD）给社区带来了身体和心理社会危害，这可能会导致青少年的心理社会压力，并增加内化障碍的风险，常见的和有影响力的健康结果。评价180天复合UNGD活动指标与新发内化障碍之间的相关性，包括焦虑和抑郁障碍的总体和单独评估，以及按性别进行的效应调整。从2008年到2016年，我们在宾夕法尼亚州的38个县使用了嵌套病例对照设计，使用了青少年Geisinger受试者的电子健康记录。病例定义为至少有两个诊断或药物医嘱表明新发内化障碍，对照组在年龄、性别和年份上频率匹配为4：1。为了评估协会，我们使用广义估计方程，与logit链接，稳健的标准误，和社区内的可交换的相关结构。我们确定了7，974名青少年（65.9%为女性，平均年龄15.0岁）新发内化障碍。当我们使用整个研究期间的数据时，没有任何关联。当仅限于UNGD活动较高的年份（2010-2016年）时，比较最高和最低四分位数，UNGD活动与新发内化障碍相关（比值比[95%置信水平]）（1.15 [1.06，1.25]）。与抑郁症的关联稍强。仅在女性中存在相关性（p = 0.009）。这是联合国全球发展战略第一次对青少年心理健康进行流行病学研究，这是对联合国全球发展战略的环境和社区影响的潜在易感群体的一个重要健康结果。在UNGD活跃地区的这一大样本中，UNGD活动与女性新发内化障碍相关。
Unconventional natural gas development (UNGD) introduces physical and psychosocial hazards into communities, which could contribute to psychosocial stress in adolescents and an increased risk of internalizing disorders, common and impactful health outcomes. To evaluate associations between a 180-day composite UNGD activity metric and new onset of internalizing disorders, overall and separately for anxiety and depressive disorders, and effect modification by sex. We used a nested case-control design from 2008 to 2016 in 38 Pennsylvania counties using electronic health records from adolescent Geisinger subjects. Cases were defined by at least two diagnoses or medication orders indicating new onset of an internalizing disorder, and controls frequency-matched 4:1 on age, sex, and year. To evaluate associations, we used generalized estimating equations, with logit link, robust standard errors, and an exchangeable correlation structure within community. We identified 7,974 adolescents (65.9% female, mean age 15.0 years) with new onset internalizing disorders. There were no associations when we used data from the entire study period. When restricted to years with higher UNGD activity (2010-2016), comparing the highest to lowest quartile, UNGD activity was associated (odds ratio [95% confidence level]) with new onset internalizing disorders (1.15 [1.06, 1.25]). Associations were slightly stronger for depressive disorders. Associations were only present in females (p = 0.009). This is the first epidemiologic study of UNGD in relation to adolescent mental health, an important health outcome in a potentially susceptible group to the environmental and community impacts of UNGD. UNGD activity was associated with new onset internalizing disorders in females in this large sample in an area of active UNGD.
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影响因子：
4.6
作者：
Eaton NR;Keyes KM;Krueger RF;Balsis S;Skodol AE;Markon KE;Grant BF;Hasin DS
通讯作者：
Hasin DS
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影响因子：
7.4
作者：
Bangasser, Debra A.;Valentino, Rita J.
通讯作者：
Valentino, Rita J.
DOI：
10.1016/j.pbj.2017.03.003
发表时间：
2017-09-01
期刊：
Porto biomedical journal
影响因子：
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作者：
Bento, Gabriela;Dias, Gisela
通讯作者：
Dias, Gisela
DOI：
10.1097/ede.0000000000000387
发表时间：
2016-03
期刊：
Epidemiology (Cambridge, Mass.)
影响因子：
--
作者：
Casey JA;Savitz DA;Rasmussen SG;Ogburn EL;Pollak J;Mercer DG;Schwartz BS
通讯作者：
Schwartz BS
DOI：
10.1016/j.jadohealth.2017.10.008
发表时间：
2018-04
期刊：
The Journal of adolescent health : official publication of the Society for Adolescent Medicine
影响因子：
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作者：
Bezold CP;Banay RF;Coull BA;Hart JE;James P;Kubzansky LD;Missmer SA;Laden F
通讯作者：
Laden F