Pixel imaging mass spectrometry with fast silicon detectors

Pixel imaging mass spectrometry with fast silicon detectors
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使用快速硅探测器进行像素成像质谱分析

DOI:
10.1016/j.nima.2010.06.178
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发表时间:
2011
期刊:
Accelerators, Spectrometers, Detectors and Associated Equipment
影响因子:
--
通讯作者:
Nomerotski A
Nomerotski A
中科院分区:
--
文献类型:
--
作者:
Nomerotski A

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We report on ‘proof of concept’ experiments in pixel imaging mass spectrometry (PImMS) using an ultra-fast frame-transfer CCD camera. The fast framing CCD camera is capable of recording and storing on-chip up to 16 separate images corresponding to different mass fragments, with a time resolution of 10ns. In addition to the standard mass spectrum, the technique allows recording of the spatial or velocity distributions of the ions at their point of formation within the instrument. Our results unambiguously demonstrate the feasibility of technique, but it is also clear that the CCD camera restricts the total number of masses that may be imaged to an unacceptably small number. We describe possible CMOS pixel detectors capable of considerably improving the achieved performance in order to meet the demanding requirements for complete recording of mass spectra of complex organic molecules.
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