Topographic organization of the cerebral cortex and brain cartography.

Topographic organization of the cerebral cortex and brain cartography.
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大脑皮层的地形组织和脑制图。

DOI:
10.1016/j.neuroimage.2017.02.018
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发表时间:
2018-04-15
期刊:
影响因子:
5.7
通讯作者:
Yeo BTT
Yeo BTT
中科院分区:
医学1区
文献类型:
--
作者:
Eickhoff SB;Constable RT;Yeo BTT

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大脑最具体但也最具挑战性的特性之一是其地形组织成不同的模块或皮层区域。本文首先回顾了地形组织的概念及其历史发展。接下来,我们提供了一个关键的讨论,目前的定义是什么构成了一个皮质区,为什么这个概念一直是如此中央的神经影像学领域和挑战,从这个观点。在这个讨论中的一个关键方面是大脑中的空间尺度和层次的问题。专注于在体内脑parcellation作为一个迅速扩大的研究领域,我们强调了潜在的局限性的经典概念的皮层区域的背景下,多模态parcellation,并提出了一个修订后的解释皮层区域的概念上的神经生物原子,可以聚合成更大的单位内和跨模态。最后,我们提出了一个展望,这一修订后的概念,为未来的映射研究的影响,并提出了一些悬而未决的问题,在大脑parcellation的背景下。
One of the most specific but also challenging properties of the brain is its topographic organization into distinct modules or cortical areas. In this paper, we first review the concept of topographic organization and its historical development. Next, we provide a critical discussion of the current definition of what constitutes a cortical area, why the concept has been so central to the field of neuroimaging and the challenges that arise from this view. A key aspect in this discussion is the issue of spatial scale and hierarchy in the brain. Focusing on in-vivo brain parcellation as a rapidly expanding field of research, we highlight potential limitations of the classical concept of cortical areas in the context of multi-modal parcellation and propose a revised interpretation of cortical areas building on the concept of neurobiological atoms that may be aggregated into larger units within and across modalities. We conclude by presenting an outlook on the implication of this revised concept for future mapping studies and raise some open questions in the context of brain parcellation.
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