Abnormal Propagation Pattern of Duodenal Pressure Waves in the Irritable Bowel Syndrome (IBS)
Abnormal Propagation Pattern of Duodenal Pressure Waves in the Irritable Bowel Syndrome (IBS)
复制标题
肠易激综合征 (IBS) 中十二指肠压力波的异常传播模式
DOI：
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发表时间：
2000
影响因子：
3.1
通讯作者：
E. Bjornsson
中科院分区：
文献类型：
--
作者：
M. Simrén;M. Castedal;J. Svedlund;H. Abrahamsson;E. Bjornsson
肠易激综合征患者胃十二指肠区单个压力波的传播模式尚不清楚。我们对26例以腹泻为主的IBS- 13 （IBS- d）和13例以便秘为主的IBS （IBS- c）患者以及32名健康对照者进行了肛肠空肠压力测量。38%的患者在常规测压评估中发现神经性运动异常。通过高分辨率分析，在大多数患者中观察到额外的异常，在IBS亚组和IBS- d的II期中，餐后逆行压力波的频率增加。主观胃肠道症状与IBS-D II期逆行压力波频率之间存在相关性。与对照组相比，患者的运动指数和长簇的数量也更高。综上所述，IBS患者个体十二指肠压力波的异常传播模式被证实，并被发现与腹泻为主的IBS症状严重程度有关。高分辨率分析为标准测压增加了信息。
The propagation pattern of individual pressure waves in the gastroduodenal area in IBS is unexplored. We performed antroduodenojejunal manometry on 26 patients with IBS—13 with diarrhea predominant IBS (IBS-D) and 13 with constipation predominant IBS (IBS-C)—and 32 healthy controls. Neuropathic-like motor abnormalities were found in 38% of the patients with conventional manometric evaluation. With high-resolution analysis additional abnormalities were observed in the majority of the patients, with increased frequency of retrograde pressure waves postprandially in both IBS subgroups and in phase II in IBS-D. A correlation between subjective gastrointestinal symptoms and the frequency of retrograde pressure waves in phase II in IBS-D was demonstrated. Motility indices and the number of long clusters were also higher in patients compared to controls. To conclude, an abnormal propagation pattern of individual duodenal pressure waves in IBS patients was demonstrated and found to be related to symptom severity in diarrhea-predominant IBS. High-resolution analysis adds information to standard manometry.
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影响因子：
29.4
作者：
DROSSMAN, DA;MCKEE, DC;BURGER, AL
通讯作者：
BURGER, AL
影响因子：
24.5
作者：
WHITEHEAD, WE;CROWELL, MD;SCHUSTER, MM
通讯作者：
SCHUSTER, MM
小肠运动活动与分泌性腹泻转运之间的关系。
DOI：
10.1152/ajpgi.1990.259.3.g420
发表时间：
1990
期刊：
The American journal of physiology
影响因子：
--
作者：
Cowles,VE;Sarna,SK
通讯作者：
Sarna,SK
影响因子：
29.4
作者：
W. Whitehead;L. Bosmajian;A. Zonderman;P. Costa;M. Schuster
通讯作者：
W. Whitehead;L. Bosmajian;A. Zonderman;P. Costa;M. Schuster
影响因子：
29.4
作者：
KELLOW, JE;PHILLIPS, SF
通讯作者：
PHILLIPS, SF