Near-infrared squaric acid derivative nanoparticles as a versatile platform for photothermal tumor cells ablation and photoacoustic imaging

Near-infrared squaric acid derivative nanoparticles as a versatile platform for photothermal tumor cells ablation and photoacoustic imaging
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近红外方酸衍生物纳米颗粒作为光热肿瘤细胞消融和光声成像的多功能平台

DOI:
10.1016/j.dyepig.2020.108670
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发表时间:
2020-11
期刊:
影响因子:
4.5
通讯作者:
Chunchang Zhao
Chunchang Zhao
中科院分区:
材料科学2区
文献类型:
--
作者:
Yin Ren;Ge Xu;Rongchen Wang;Tianli Zhu;Jiahui Tan;Xianfeng Gu;Chunchang Zhao

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有机纳米材料在光热癌细胞治疗方面取得了巨大进展。然而,合成具有良好水分散性和生物相容性的自组装有机材料仍然是一个挑战。在这里,我们设计了近红外方酸衍生纳米颗粒作为肿瘤细胞消融的多功能平台。这种自组装有机纳米粒子表现出高光热转换和强PA信号,能够成功热消融癌细胞。
Organic nanomaterials have made great progress in photothermal cancer cells therapy. However, it is still a challenge to synthesize self-assembled organic materials with good water dispersity and biocompatibility. Here, we designed near-infrared squaric acid derivatived nanoparticles as a versatile platform for tumor cells ablation. Such self-assembled organic nanaoparticles showed high photothermal conversion and strong PA signals, enabling the successful thermal abaltion of cancer cells.
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