Genetic characterization of foot-and-mouth disease viruses, Ethiopia, 1981-2007.
Genetic characterization of foot-and-mouth disease viruses, Ethiopia, 1981-2007.
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DOI:
10.3201/eid1509.090091
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发表时间:
2009-09
影响因子:
11.8
通讯作者:
Knowles NJ
中科院分区:
文献类型:
--
作者:
Ayelet G;Mahapatra M;Gelaye E;Egziabher BG;Rufeal T;Sahle M;Ferris NP;Wadsworth J;Hutchings GH;Knowles NJ
Virus diversity indicates a virus reservoir in this country. Foot-and-mouth disease (FMD) is endemic to sub-Saharan Africa. To further understand its complex epidemiology, which involves multiple virus serotypes and host species, we characterized the viruses recovered from FMD outbreaks in Ethiopia during 1981–2007. We detected 5 of the 7 FMDV serotypes (O, A, C, Southern African Territories [SAT] 1, and SAT 2). Serotype O predominated, followed by serotype A; type C was not recognized after 1983. Phylogenetic analysis of virus protein 1 sequences indicated emergence of a new topotype within serotype O, East Africa 4. In 2007, serotype SAT 1 was detected in Ethiopia and formed a new distinct topotype (IX), and serotype SAT 2 reappeared after an apparent gap of 16 years. The diversity of viruses highlights the role of this region as a reservoir for FMD virus, and their continuing emergence in Ethiopia will greatly affect spread and consequent control strategy of the disease on this continent.
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影响因子:
5.5
作者:
Mattion, N;König, G;Palma, EL
通讯作者:
Palma, EL
影响因子:
2.7
作者:
Sahle, M.;Dwarka, R. M.;Vosloo, W.
通讯作者:
Vosloo, W.
影响因子:
1.7
作者:
Megersa, B.;Beyene, B.;Rufael, T.
通讯作者:
Rufael, T.
影响因子:
1.7
作者:
ROEDER, PL;ABRAHAM, G;KITCHING, RP
通讯作者:
KITCHING, RP
影响因子:
2.4
作者:
ROEDER, PL;SMITH, PML
通讯作者:
SMITH, PML