One-Way Particle Transport Using Oscillatory Flow in Asymmetric Traps.

One-Way Particle Transport Using Oscillatory Flow in Asymmetric Traps.
复制标题

DOI:
10.1002/smll.201702724
复制
发表时间:
2018-03
期刊:
Small (Weinheim an der Bergstrasse, Germany)
影响因子:
--
通讯作者:
Burns MA
Burns MA
中科院分区:
其他
文献类型:
--
作者:
Lee J;Burns MA

文献摘要

参考文献

被引文献

相似文献

将被动的微粒操纵技术集成到多功能微流体装置中的一个挑战是将大多数系统的连续流形式与颗粒分离系统的通常分批式操作相结合。在这里,我们提出了一种被动的流体技术-单向粒子传输-可以进行微粒子操作在一个封闭的流体回路。利用微颗粒和非对称阱之间的传递/捕获相互作用,该技术实现了振荡流场中颗粒的净位移。单向粒子输运是通过四种陷阱-粒子相互作用实现的:粒子的机械捕获,陷阱和粒子之间的不对称相互作用,粒子与障碍物的物理碰撞,以及粒子横向移动到粒子捕获流中。这四个条件的临界尺寸被发现通过数值求解解析的质量平衡方程,制定使用周期性障碍物阵列的流场特性。对低雷诺数(<0.01)流动中实验捕获颗粒动力学的直观观察证实了理论预测的有效性。该技术可以在仅几次流体振荡(每次振荡<500 ms)中将数百个微粒输送穿过陷阱行,并通过它们的尺寸差异分离颗粒。
One challenge of integrating of passive, micro-particles manipulation techniques into multifunctional microfluidic devices is coupling the continuous-flow format of most systems with the often batch-type operation of particle separation systems. Here we present a passive fluidic technique — one-way particle transport — that can conduct micro-particle operations in a closed fluidic circuit. Exploiting pass/capture interactions between micro-particles and asymmetric traps, this technique accomplishes a net displacement of particles in an oscillatory flow field. One-way particle transport is achieved through four kinds of trap-particle interactions: mechanical capture of the particle, asymmetric interactions between the trap and the particle, physical collision of the particle with an obstacle, and lateral shift of the particle into a particle-trapping stream. The critical dimensions for those four conditions are found by numerically solving analytical mass balance equations formulated using the characteristics of the flow field in periodic obstacle arrays. Visual observation of experimental trap-particle dynamics in low Reynolds number flow (<0.01) confirms the validity of the theoretical predictions. This technique can transport hundreds of micro-particles across trap rows in only a few fluid oscillations (<500 ms per oscillation) and separate particles by their size differences.
惯性微流体电池担架(IMC):完全自动化,高通量和接近实时的细胞机械分型。
DOI: 10.1002/smll.201700705
发表时间: 2017-07
期刊: Small (Weinheim an der Bergstrasse, Germany)
影响因子: --
作者:
Deng Y;Davis SP;Yang F;Paulsen KS;Kumar M;Sinnott DeVaux R;Wang X;Conklin DS;Oberai A;Herschkowitz JI;Chung AJ
通讯作者: Chung AJ
DOI: 10.1103/revmodphys.83.647
发表时间: 2011-06-20
影响因子: 44.1
作者:
Friend, James;Yeo, Leslie Y.
通讯作者: Yeo, Leslie Y.
DOI: 10.1039/b701227f
发表时间: 2007-01-01
期刊: LAB ON A CHIP
影响因子: 6.1
作者:
Choi, Sungyoung;Park, Je-Kyun
通讯作者: Park, Je-Kyun
DOI: 10.1126/science.1094567
发表时间: 2004-05-14
期刊: SCIENCE
影响因子: 56.9
作者:
Huang, LR;Cox, EC;Sturm, JC
通讯作者: Sturm, JC
DOI: 10.1002/smll.201200588
发表时间: 2012-09-10
期刊: SMALL
影响因子: 13.3
作者:
Gossett, Daniel R.;Tse, Henry Tat Kwong;Di Carlo, Dino
通讯作者: Di Carlo, Dino