Bronchial hyper-responsiveness after human cardiopulmonary transplantation.
Bronchial hyper-responsiveness after human cardiopulmonary transplantation.
复制标题
人心肺移植后支气管高反应性。
DOI:
10.1042/cs0730299
复制
发表时间:
1987
期刊:
影响因子:
--
通讯作者:
Robin,ED
中科院分区:
文献类型:
--
作者:
Glanville,AR;Burke,CM;Theodore,J;Baldwin,JC;Harvey,J;Vankessel,A;Robin,ED
1. Bronchial responsiveness to inhaled methacholine was studied in ten heart-lung transplant (HLT) recipients a mean 10.6 months (range 1.5-28 months) post-HLT and in ten normal subjects. 2. The mean provocation dose of methacholine producing a 20% fall in FEV1 (PD20 FEV1) was significantly lower in the HLT recipients (1.70+/-3.96 mg vs 11.55+/-3.79 mg; P less than 0.001), as was the mean provocation dose of methacholine producing a 50% fall in specific airway conductance (PD50 sGAW)(0.08+/-0.08 mg vs 5.13+/-5.47 mg; P less than 0.005). 3. These results establish the presence of significant bronchial hyper-responsiveness to inhaled cholinergic agonists in the transplanted lung.
影响因子:
6.2
作者:
BA A. C. WALLACE;MD R. C. Nairn
通讯作者:
MD R. C. Nairn
影响因子:
7.8
作者:
Ben-Ze'ev, A
通讯作者:
Ben-Ze'ev, A
DOI:
--
发表时间:
1987
期刊:
Laboratory investigation; a journal of technical methods and pathology
影响因子:
--
作者:
S. Pitz;R. Moll;S. Störkel;W. Thoenes
通讯作者:
W. Thoenes