Flavonoid scutellarin positively regulates root length through NUTCRACKER.

Flavonoid scutellarin positively regulates root length through NUTCRACKER.
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黄酮类灯盏乙素通过 NUTCRACKER 积极调节根长

DOI:
10.1016/j.pld.2020.08.001
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发表时间:
2021-06
期刊:
影响因子:
4.8
通讯作者:
Zhang X
Zhang X
中科院分区:
生物学2区
文献类型:
--
作者:
Huang X;Li W;Zhang X

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探索调控分生组织的方法具有特殊的重要性和广泛的兴趣。在这项研究中,我们发现,类黄酮灯盏乙素,其中有一个6-羟基和7-葡萄糖苷,通过转录因子NUTCRACKER(NUC)增加根长。这种根伸长在NUC敲除中消失,并在NUC拯救植物中重新出现。灯盏乙素诱导NUC表达,促进皮层/内胚层原始细胞的分裂。相比之下,具有相同化学骨架但不具有6-羟基和具有7-羟基的柚皮素表现出相反的作用或没有作用。我们的研究结果表明,野黄芩素促进根长通过NUC介导的调节途径,并揭示,黄酮类化合物与6-羟基和7-葡萄糖苷和没有分生组织的大小,分别有积极和消极的影响。
Exploring approaches to regulate meristem is of special importance and broad interest. In this study, we found that the flavonoid scutellarin, which has a 6-hydroxyl and a 7-glucoside, increased root length through the transcription factor NUTCRACKER (NUC). This root lengthening disappeared in NUC-knockout and reappeared in NUC-rescue plants. Scutellarin induced NUC expression and promoted the division of cortex/endodermal initials. In contrast, naringenin, which has same chemical backbone but without 6-hydroxyl and with 7-hydroxyl group, showed the opposite or no effects. Our results demonstrate that scutellarin promotes root length through NUC-mediated regulatory pathways and reveal that flavonoids with and without the 6-hydroxyl and 7-glucoside have positive and negative effects on meristem size, respectively.
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