Wide spread cross resistance to pyrethroids in Aedes aegypti (Diptera: Culicidae) from Veracruz state Mexico.
Wide spread cross resistance to pyrethroids in Aedes aegypti (Diptera: Culicidae) from Veracruz state Mexico.
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DOI：
10.1603/ec12284
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发表时间：
2013-04
影响因子：
2.2
通讯作者：
Black WC 4th
中科院分区：
文献类型：
--
作者：
Flores AE;Ponce G;Silva BG;Gutierrez SM;Bobadilla C;Lopez B;Mercado R;Black WC 4th
采用瓶法测定7株F1型埃及伊蚊对拟除虫菊酯、氯菊酯、溴氰菊酯、λ-氰氰菊酯、联苯菊酯、高效氯氰菊酯、α-高效氯氰菊酯和z型氯氰菊酯的抗性。新奥尔良菌株被用作易感对照。测定暴露1小时后和恢复期24小时后的死亡率。F1毒株和新奥尔良毒株50%敲除值（RRKC50）的抗性比表明其具有较高的敲除抗性（kdr）。α-氯氰菊酯的RRKC50值在10 ~ 100之间，表明kdr水平较高。大多数菌株对d-吩菊酯具有中等抗性。对λ -氯氰菊酯、氯氰菊酯和氯氰菊酯的抗性水平显著但较低。对氯氰菊酯和联苯菊酯均有1株抗性，RRKC50值分别为10倍和21倍。3株菌株对溴氰菊酯呈中等抗性，其余菌株对溴氰菊酯呈敏感。除d-吩菊酯外，所有菌株的蚊虫对拟除虫菊酯类杀虫剂均有一定的恢复。采用回归分析RRLC50和RRKC50之间的关系。两者高度相关（R2 = 0.84 - 0.97），因此斜率可用于确定需要添加多少拟除虫菊酯类杀虫剂才能确保致死性。d-吩氰菊酯（RRLC50）的斜率为0.875，λ -氰氰菊酯的斜率为8.67。除联苯菊酯外，其余拟除虫菊酯的RRLC50和RRKC50呈高度相关，具有较强的交叉抗性。联苯菊酯似乎是一种替代拟除虫菊酯，没有很强的交叉抗性，可以替代目前在墨西哥广泛使用的氯菊酯。
Seven F1 strains of Aedes aegypti (L.) were evaluated by bottle bioassay for resistance to the pyrethroids d-phenothrin, permethrin, deltamethrin, λ-cyalothrin, bifenthrin, cypermethrin, α-cypermethrin and z-cypermethrin. The New Orleans strain was used as a susceptible control. Mortality rates after a 1h exposure and following a 24h recovery period were determined. The resistance ratio between the 50% knockdown values (RRKC50) of the F1 and New Orleans strains indicated high levels of knockdown resistance (kdr). The RRKC50 with α-cypermethrin varied from 10–100 among strains indicating high levels of kdr. Most of the strains had moderate resistance to d-phenothrin. Significant but much lower levels of resistance were detected for λ–cyalothrin, permethrin and cypermethrin. For z-cypermethrin and bifenthrin, only one strain exhibited resistance with RRKC50 values of 10- and 21-fold, respectively. None of the strains showed RRKC50 >10 with deltamethrin, and moderate resistance was seen in three strains, while the rest were susceptible. Mosquitoes from all strains exhibited some recovery from all pyrethroids except d-phenothrin. Regression analysis was used to analyze the relationship between RRLC50 and RRKC50. Both were highly correlated (R2 = 0.84 – 0.97) so that the slope could be used to determine how much additional pyrethroid was needed to insure lethality. Slopes ranged from 0.875 for d-phenothrin (RRLC50 ≃ RRKC50) to 8.67 for λ–cyalothrin (~8.5 fold more insecticide needed to kill). Both RRLC50 and RRKC50 values were highly correlated for all pyrethroids except bifenthrin indicating strong cross resistance. Bifenthrin appears to be an alternative pyrethroid without strong cross resistance that could be used as an alternative to the current widespread use of permethrin in Mexico.
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影响因子：
1.9
作者：
Brengues, C;Hawkes, NJ;Hemingway, J
通讯作者：
Hemingway, J
影响因子：
0.4
作者：
Flores, Adriana E.;Reyes Solis, Guadalupe;Ponce Garcia, Gustavo
通讯作者：
Ponce Garcia, Gustavo
DOI：
10.1111/j.1095-8312.1993.tb00873.x
发表时间：
1993-01-01
影响因子：
1.9
作者：
CURTIS, CF;HILL, N;KASIM, SH
通讯作者：
KASIM, SH
DOI：
10.1590/s0074-02762004000200015
发表时间：
2004-03-01
期刊：
Memórias do Instituto Oswaldo Cruz
影响因子：
--
作者：
Braga, Ima Aparecida;Lima, José Bento Pereira;Valle, Denise
通讯作者：
Valle, Denise
影响因子：
1.9
作者：
HEMINGWAY, J;BODDINGTON, RG;DUNBAR, SJ
通讯作者：
DUNBAR, SJ