Decomposing Executive Function into Distinct Processes Underlying Human Decision Making

Decomposing Executive Function into Distinct Processes Underlying Human Decision Making
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将执行功能分解为人类决策背后的不同流程

DOI:
10.1109/embc48229.2022.9871849
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发表时间:
2022
期刊:
2022 44th Annual International Conference of the IEEE Engineering in Medicine & Biology Society (EMBC
影响因子:
--
通讯作者:
Sarma, Sridevi V.
Sarma, Sridevi V.
中科院分区:
--
文献类型:
--
作者:
Dorman, Daniel B.;Sampson, Aaron L.;Sacre, Pierre;Stuphorn, Veit;Niebur, Ernst;Sarma, Sridevi V.

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执行功能(EF)由更高层次的认知过程组成,包括工作记忆、认知灵活性和抑制,这些过程共同促成了目标导向的行为。许多神经疾病与EF功能障碍有关,这可能导致行为不佳。为了评估这些过程的作用,我们引入了一种新的行为任务和建模方法。这项类似赌博的任务具有针对不同EF能力的子任务,允许对EF的主要组成部分进行定量评估。我们证明,人类参与者在EF的组成过程中表现出可分离的可变性。这些结果将使我们能够在未来的工作中将行为结果与脑电记录相对应,以便绘制与EF缺陷相关的大脑网络图。临床相关性-这项工作将使我们能够在未来的工作中量化EF缺陷和患者群体中相应的脑活动。
Executive function (EF) consists of higher level cognitive processes including working memory, cognitive flexibility, and inhibition which together enable goal-directed behaviors. Many neurological disorders are associated with EF dysfunctions which can lead to suboptimal behavior. To assess the roles of these processes, we introduce a novel behavioral task and modeling approach. The gamble-like task, with sub-tasks targeting different EF capabilities, allows for quantitative assessment of the main components of EF. We demonstrate that human participants exhibit dissociable variability in the component processes of EF. These results will allow us to map behavioral outcomes to EEG recordings in future work in order to map brain networks associated with EF deficits. Clinical relevance— This work will allow us to quantify EF deficits and corresponding brain activity in patient populations in future work.
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