Impact of the CamAPS FX hybrid closed-loop insulin delivery system on sleep traits in older adults with type 1 diabetes.

Impact of the CamAPS FX hybrid closed-loop insulin delivery system on sleep traits in older adults with type 1 diabetes.
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Camaps FX混合闭合环胰岛素输送系统对1型糖尿病老年人睡眠特征的影响。

DOI:
10.1111/dom.14914
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发表时间:
2023-03
期刊:
Diabetes, obesity & metabolism
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其他
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获得健康的睡眠支持整体健康和幸福1,2。1型糖尿病(T1 DM)的睡眠障碍可能是由担心低血糖和血糖控制不佳等因素引起的。例如,低血糖或高血糖可分别通过交感神经激活和神经病理性疼痛等机制干扰睡眠。一些观察性研究表明,混合闭环系统的启动与改善睡眠有关,5,6,但这些数据可能会受到混淆和其他偏见的限制。此外,不同的HCL设备可能对睡眠有不同的影响;结果可能会受到用户年龄和评估睡眠的标准的影响。在老年T1 DM患者中,我们的目标是:a)通过对随机对照试验(RCT)数据的事后分析,评估适应性HCL系统(CamAPS FX)对主观和客观评估睡眠特征的影响;以及b)在试验队列中评估血糖控制与睡眠特征之间的关系。
Achieving healthy sleep supports general health and well-being1, 2. Sleep disturbance in type 1 diabetes (T1DM) can be caused by factors including fear of hypoglycaemia and suboptimal glucose control3. For example, hypoglycaemia or hyperglycaemia can disturb sleep, through mechanisms including sympathetic activation and neuropathic pain, respectively4. Several observational studies have suggested that hybrid closed-loop (HCL) system initiation is associated with improved sleep, 5, 6 but these data could be limited by confounding and other biases. Moreover, different HCL devices could have differing effects on sleep; outcomes could be influenced by user age and the measures by which sleep is assessed. Our objectives, in older adults with T1DM, were to: a) assess the impact of an adaptive HCL system (CamAPS FX) on subjectively and objectively assessed sleep traits in a post hoc analysis of randomised controlled trial (RCT) data; and b) assess the relationship between glucose control and sleep traits in the trial cohort.
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发表时间: 2021-11-01
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影响因子: --
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