Ancillary Activity: Beyond Core Metabolism in Immune Cells.

Ancillary Activity: Beyond Core Metabolism in Immune Cells.
复制标题

DOI:
10.1016/j.cmet.2017.06.019
复制
发表时间:
2017-07-05
期刊:
影响因子:
29
通讯作者:
Pearce EL
Pearce EL
中科院分区:
生物学1区
文献类型:
--
作者:
Puleston DJ;Villa M;Pearce EL

文献摘要

参考文献

被引文献

相似文献

免疫细胞的功能和命运与代谢途径的参与密切相关。近年来,核心代谢途径在免疫细胞生物能量学中的作用得到了广泛的研究。然而,除了能量产生之外,其他外周代谢途径是如何支持免疫细胞的,目前还不太清楚。在这里,我们回顾了文献并强调了我们对几种辅助代谢途径的理解的最新进展,以及它们如何支持ATP生产之外的过程并最终促进保护性免疫。
Immune cell function and fate is intimately linked to engagement of metabolic pathways. The contribution of core metabolic pathways to immune cell bioenergetics has been vigorously investigated in recent years. However, precisely how other peripheral metabolic pathways support immune cells beyond energy generation is less well understood. Here we survey the literature and highlight recent advances in our understanding of several ancillary metabolic pathways and how they support processes beyond ATP production and ultimately contribute to protective immunity.
DOI: 10.1084/jem.20121061
发表时间: 2012-11-19
期刊: The Journal of experimental medicine
影响因子: --
作者:
Austin WR;Armijo AL;Campbell DO;Singh AS;Hsieh T;Nathanson D;Herschman HR;Phelps ME;Witte ON;Czernin J;Radu CG
通讯作者: Radu CG
DOI: 10.1016/j.immuni.2012.11.004
发表时间: 2013-01-24
期刊: Immunity
影响因子: 32.4
作者:
Blanc M;Hsieh WY;Robertson KA;Kropp KA;Forster T;Shui G;Lacaze P;Watterson S;Griffiths SJ;Spann NJ;Meljon A;Talbot S;Krishnan K;Covey DF;Wenk MR;Craigon M;Ruzsics Z;Haas J;Angulo A;Griffiths WJ;Glass CK;Wang Y;Ghazal P
通讯作者: Ghazal P
DOI: 10.1083/jcb.201501101
发表时间: 2015-03-30
期刊: The Journal of cell biology
影响因子: --
作者:
Bond MR;Hanover JA
通讯作者: Hanover JA
DOI: 10.1038/nature08155
发表时间: 2009-07-02
期刊: NATURE
影响因子: 64.8
作者:
Araki, Koichi;Turner, Alexandra P.;Shaffer, Virginia Oliva;Gangappa, Shivaprakash;Keller, Susanne A.;Bachmann, Martin F.;Larsen, Christian P.;Ahmed, Rafi
通讯作者: Ahmed, Rafi
DOI: 10.1016/j.molcel.2010.06.022
发表时间: 2010-07-30
期刊: Molecular cell
影响因子: 16
作者:
Düvel K;Yecies JL;Menon S;Raman P;Lipovsky AI;Souza AL;Triantafellow E;Ma Q;Gorski R;Cleaver S;Vander Heiden MG;MacKeigan JP;Finan PM;Clish CB;Murphy LO;Manning BD
通讯作者: Manning BD