Deoxynivalenol: a major player in the multifaceted response of Fusarium to its environment.
Deoxynivalenol: a major player in the multifaceted response of Fusarium to its environment.
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DOI：
10.3390/toxins6010001
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发表时间：
2013-12-19
期刊：
影响因子：
4.2
通讯作者：
Haesaert G
中科院分区：
文献类型：
--
作者：
Audenaert K;Vanheule A;Höfte M;Haesaert G
由几种镰刀菌属产生的真菌毒素脱氧雪腐镰刀菌烯醇（DON），作为一种毒力因子，是小麦感染后症状发展的关键。越来越多的证据表明，这种次级代谢产物的产生可以由不同的环境和细胞信号触发，这意味着它可能在真菌的生命周期中发挥额外的作用。在这里，我们回顾的数据，位置DON在镰孢菌的saparitic健身，在国防和植物和真菌的主要C和N代谢。我们结合联合收割机的推测模型中的作用DON在整个与主机的相互作用，提供工作假设，等待实验验证。我们还强调了在该领域的控制措施对DON生产的可能影响，并总结了食品和饲料基质加工和储存过程中非生物因素的影响。总之，我们可以得出结论，DON是镰刀菌科普不断变化的环境，并确保其在不同情况下的生长，存活和产生有毒代谢产物的一个非常重要的化合物。
The mycotoxin deoxynivalenol (DON), produced by several Fusarium spp., acts as a virulence factor and is essential for symptom development after initial wheat infection. Accumulating evidence shows that the production of this secondary metabolite can be triggered by diverse environmental and cellular signals, implying that it might have additional roles during the life cycle of the fungus. Here, we review data that position DON in the saprophytic fitness of Fusarium, in defense and in the primary C and N metabolism of the plant and the fungus. We combine the available information in speculative models on the role of DON throughout the interaction with the host, providing working hypotheses that await experimental validation. We also highlight the possible impact of control measures in the field on DON production and summarize the influence of abiotic factors during processing and storage of food and feed matrices. Altogether, we can conclude that DON is a very important compound for Fusarium to cope with a changing environment and to assure its growth, survival, and production of toxic metabolites in diverse situations.
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影响因子：
4.9
作者：
Desmond, Olivia J.;Manners, John M.;Kazan, Kemal
通讯作者：
Kazan, Kemal
影响因子：
4.4
作者：
Edwards, SG;Pirgozliev, SR;Jenkinson, P
通讯作者：
Jenkinson, P
影响因子：
4.2
作者：
Audenaert K;Callewaert E;Höfte M;De Saeger S;Haesaert G
通讯作者：
Haesaert G
农艺和气候因素对挪威谷物镰刀菌侵染和霉菌毒素污染的影响。
DOI：
10.1080/19440049.2012.672476
发表时间：
2012
期刊：
Food additives & contaminants. Part A, Chemistry, analysis, control, exposure & risk assessment
影响因子：
--
作者：
Bernhoft A;Torp M;Clasen PE;Løes AK;Kristoffersen AB
通讯作者：
Kristoffersen AB
影响因子：
5.3
作者：
Gardiner DM;Kazan K;Praud S;Torney FJ;Rusu A;Manners JM
通讯作者：
Manners JM