Stage and load effects on ERP topography during verbal and spatial working memory.
Stage and load effects on ERP topography during verbal and spatial working memory.
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DOI：
10.1016/j.brainres.2008.11.063
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发表时间：
2009-02-13
期刊：
影响因子：
2.9
通讯作者：
Shucard DW
中科院分区：
文献类型：
--
作者：
Shucard JL;Tekok-Kilic A;Shiels K;Shucard DW
额顶神经网络在视觉工作记忆的功能组织中起着重要作用。材料特定信息的相对贡献（例如，言语或空间）对WM回路激活的影响还没有完全理解。工作记忆的特定加工模型认为，工作记忆回路的激活更多地依赖于工作记忆的阶段，而不是加工的信息类型。本研究探讨了工作记忆信息类型（言语、空间）、阶段（编码、维持）和负荷对事件相关电位（ERP）P3波幅的前后位分布和偏侧头皮分布的影响。17名年轻人进行了等同于刺激特性和反应要求的言语和空间任务。这两个任务都是在1-和3-负载条件下提出的。P3波幅在左半球、中线和右半球头皮位置的前后地形图受工作记忆阶段和记忆负荷的影响，但不受信息类型的影响。编码阶段表现出最小的负荷效应，并与后验最大P3振幅分布。在维护阶段，探针字母是无关的先前编码的刺激。在这里，较高的WM负载产生相对较大的额叶和减少顶叶P3振幅相比，较低的WM负载。这些编码和维护的前-后P3振幅模式在左侧、中线和右侧位置相似。在本研究的局限性内，我们的结果倾向于支持WM电路的过程依赖性激活，因为P3振幅地形图仅作为WM阶段和负载的结果而不同，而不是由于所呈现的信息类型（言语或空间）。
Frontal-parietal neural networks play a significant role in the functional organization of visual working memory (WM). The relative contribution of material-specific information (e.g., verbal or spatial) on activation of WM circuitry is not fully understood. Process-specific models of WM propose that the activation of WM circuitry is more dependent on the stage of WM than on the type of information being processes. This study investigated the effects of WM information type (verbal, spatial), stage (encoding, maintenance), and load on both the anterior–posterior topography and lateralized scalp distributions of the event-related potential (ERP) P3 amplitude. Seventeen young adults performed verbal and spatial tasks that were equated for stimulus properties and response requirements. Both tasks were presented under 1- and 3-load conditions. The anterior–posterior topography of P3 amplitude at left hemisphere, midline, and right hemisphere scalp locations was affected by the stage of WM and the memory load, but not by the type of information. The encoding stage showed minimal load effects and was associated with a posterior-maximum P3 amplitude distribution. During the maintenance stage, probe letters were presented that were irrelevant to the previously encoded stimuli. Here, higher WM load produced relatively greater frontal and reduced parietal P3 amplitude compared to lower WM load. These anterior–posterior P3 amplitude patterns for encoding and maintenance were similar at left, midline, and right locations. Within the limitations of the study, our results tend to support a process-dependent activation of WM circuits in that P3 amplitude topography only differed as a result of WM stage and load, and not as a result of the type of information (verbal or spatial) presented.
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影响因子：
2.5
作者：
D'Esposito, M;Postle, BR;Lease, J
通讯作者：
Lease, J
DOI：
10.1016/0013-4694(96)00288-x
发表时间：
1996-04-01
期刊：
ELECTROENCEPHALOGRAPHY AND CLINICAL NEUROPHYSIOLOGY
影响因子：
--
作者：
Gevins, A;Smith, ME;Whitfield, S
通讯作者：
Whitfield, S
DOI：
10.1016/j.cogbrainres.2004.10.010
发表时间：
2005-05-01
期刊：
COGNITIVE BRAIN RESEARCH
影响因子：
--
作者：
Habeck, C;Rakitin, BC;Stern, Y
通讯作者：
Stern, Y
影响因子：
56.9
作者：
Courtney, SM;Petit, L;Haxby, JV
通讯作者：
Haxby, JV
影响因子：
3.3
作者：
Curtis, CE
通讯作者：
Curtis, CE