Stimulus-specific delay activity in human primary visual cortex.
Stimulus-specific delay activity in human primary visual cortex.
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DOI：
10.1111/j.1467-9280.2009.02276.x
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发表时间：
2009-02
影响因子：
8.2
通讯作者：
Awh E
中科院分区：
文献类型：
--
作者：
Serences JT;Ester EF;Vogel EK;Awh E
工作记忆（WM）涉及将信息保持在在线状态。一种新出现的观点认为，WM中的信息是通过感觉招募来维持的，因此信息是通过编码待记忆信息的感觉区域的持续活动来存储的。使用功能性磁共振成像，我们观察到关键的感觉区域，如初级视觉皮层（V1）在WM延迟期间显示出平均激活持续增加的证据很少，尽管这种幅度的增加通常被用来确定一个区域是否参与在线维护。然而，延迟期活动的多体素模式分析揭示了V1的持续激活模式，该模式仅代表多特征对象的故意存储特征。此外，延迟活动的模式在质量上与在感觉刺激辨别过程中观察到的模式相似，这表明V1中的WM表征是纯感觉加工过程中所唤起的表征的合理“复制”。
Working memory (WM) involves maintaining information in an on-line state. One emerging view is that information in WM is maintained via sensory recruitment, such that information is stored via sustained activity in the sensory areas that encode the to-be-remembered information. Using functional magnetic resonance imaging, we observed that key sensory regions such as primary visual cortex (V1) showed little evidence of sustained increases in mean activation during a WM delay period, though such amplitude increases have typically been used to determine whether a region is involved in on-line maintenance. However, a multivoxel pattern analysis of delay-period activity revealed a sustained pattern of activation in V1 that represented only the intentionally stored feature of a multifeature object. Moreover, the pattern of delay activity was qualitatively similar to that observed during the discrimination of sensory stimuli, suggesting that WM representations in V1 are reasonable “copies” of those evoked during pure sensory processing.
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影响因子：
9.2
作者：
Kamitani, Yukiyasu;Tong, Frank
通讯作者：
Tong, Frank
DOI：
10.1016/s0926-6410(00)00056-2
发表时间：
2001-01-01
期刊：
COGNITIVE BRAIN RESEARCH
影响因子：
--
作者：
Druzgal, TJ;D'Esposito, M
通讯作者：
D'Esposito, M
DOI：
10.1037/0278-7393.18.2.307
发表时间：
1992-03-01
影响因子：
2.6
作者：
IRWIN, DE
通讯作者：
IRWIN, DE
影响因子：
9.2
作者：
Martinez-Trujillo, JC;Treue, S
通讯作者：
Treue, S
影响因子：
25
作者：
Kamitani, Y;Tong, F
通讯作者：
Tong, F