The strategy, organization, and progress of the HUPO Human Proteome Project.

The strategy, organization, and progress of the HUPO Human Proteome Project.
复制标题

DOI:
10.1016/j.jprot.2013.10.012
复制
发表时间:
2014-04-04
影响因子:
3.3
通讯作者:
Omenn GS
Omenn GS
中科院分区:
生物学2区
文献类型:
--
作者:
Omenn GS

文献摘要

参考文献

被引文献

相似文献

人类蛋白质组计划是人类蛋白质组组织的一项重大、全面的倡议。这项全球合作努力旨在从20,300个人类蛋白质编码基因中识别和表征至少一个蛋白质产品和许多PTM、SAP和剪接变体异构体。交付成果是一个广泛的部件清单和一系列技术平台、试剂、光谱库和链接的知识库,这些都推动了该领域的发展,并促进了更广泛的生命科学家社区对蛋白质组学的使用。这样的实现将有助于解决利用蛋白质组学弥合基因组变异证据和多样化表型之间的重大差距这一重大挑战。
The Human Proteome Project is a major, comprehensive initiative of the Human Proteome Organization. This global collaborative effort aims to identify and characterize at least one protein product and many PTM, SAP, and splice variant isoforms from the 20,300 human protein-coding genes. The deliverables are an extensive parts list and an array of technology platforms, reagents, spectral libraries, and linked knowledge bases that advance the field and facilitate the use of proteomics by a much wider community of life scientists. Such enablement will help address the Grand Challenge of using proteomics to bridge major gaps between evidence of genomic variation and diverse phenotypes.
DOI: 10.1016/j.jprot.2013.04.007
发表时间: 2013-09-02
影响因子: 3.3
作者:
Omenn, Gilbert S.;Menon, Rajasree;Zhang, Yang
通讯作者: Zhang, Yang
DOI: 10.1021/pr300830v
发表时间: 2013-01-01
影响因子: 4.4
作者:
Gaudet, Pascale;Argoud-Puy, Ghislaine;Lane, Lydie
通讯作者: Lane, Lydie
DOI: 10.1074/mcp.m111.009993
发表时间: 2011-07-01
影响因子: 7
作者:
Legrain, Pierre;Aebersold, Ruedi;Omenn, Gilbert S.
通讯作者: Omenn, Gilbert S.
DOI: 10.1038/msb.2011.82
发表时间: 2011-11-08
影响因子: 9.9
作者:
通讯作者: --
DOI: 10.1021/pr300924j
发表时间: 2013-06-01
影响因子: 4.4
作者:
Fagerberg, Linn;Oksvold, Per;Uhlen, Mathias
通讯作者: Uhlen, Mathias