DNA Origami Nanomachines.

DNA Origami Nanomachines.
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DOI:
10.3390/molecules23071766
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发表时间:
2018-07-18
期刊:
Molecules (Basel, Switzerland)
影响因子:
--
通讯作者:
Sugiyama H
Sugiyama H
中科院分区:
其他
文献类型:
--
作者:
Endo M;Sugiyama H

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DNA可以按程序组装各种分子和纳米材料,是纳米技术和生物学研究领域的有力工具。DNA还允许通过设计DNA序列来构建所需的纳米级结构。结构纳米技术,特别是DNA折纸,被广泛用于设计和创建功能化的纳米结构和设备。此外,DNA分子机器已经被创造出来,并由特定的DNA链和外部刺激来操作,以执行线性,旋转和往复运动。此外,通过精确地排列多个分子和分子机器来模拟生物系统,已经在DNA纳米结构上创建了复杂的分子系统。目前,DNA纳米机器,如分子马达,在DNA纳米结构上运行。具有机械可控系统的动态DNA纳米结构也已被开发。在这篇综述中,我们描述了新的DNA纳米机器和纳米系统,建立在设计的DNA纳米结构的最新研究。
DNA can assemble various molecules and nanomaterials in a programmed fashion and is a powerful tool in the nanotechnology and biology research fields. DNA also allows the construction of desired nanoscale structures via the design of DNA sequences. Structural nanotechnology, especially DNA origami, is widely used to design and create functionalized nanostructures and devices. In addition, DNA molecular machines have been created and are operated by specific DNA strands and external stimuli to perform linear, rotational, and reciprocating movements. Furthermore, complicated molecular systems have been created on DNA nanostructures by arranging multiple molecules and molecular machines precisely to mimic biological systems. Currently, DNA nanomachines, such as molecular motors, are operated on DNA nanostructures. Dynamic DNA nanostructures that have a mechanically controllable system have also been developed. In this review, we describe recent research on new DNA nanomachines and nanosystems that were built on designed DNA nanostructures.
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