MALDI imaging mass spectrometry: spatial molecular analysis to enable a new age of discovery.
MALDI imaging mass spectrometry: spatial molecular analysis to enable a new age of discovery.
复制标题
MALDI成像质谱法:空间分子分析以实现新的发现时代。
DOI:
10.1016/j.jprot.2014.03.021
复制
发表时间:
2014-07-31
影响因子:
3.3
通讯作者:
Caprioli RM
中科院分区:
文献类型:
--
作者:
Gessel MM;Norris JL;Caprioli RM
Matrix-assisted laser desorption/ionization imaging mass spectrometry (MALDI IMS) combines the sensitivity and selectivity of mass spectrometry with spatial analysis to provide a new dimension for histological analyses to provide unbiased visualization of the arrangement of biomolecules in tissue. As such, MALDI IMS has the capability to become a powerful new molecular technology for the biological and clinical sciences. In this review, we briefly describe several applications of MALDI IMS covering a range of molecular weights, from drugs to proteins. Current limitations and challenges are discussed along with recent developments to address these issues.
登录
查看更多内容
DOI:
10.1016/j.jasms.2009.01.017
发表时间:
2009-06
影响因子:
3.2
作者:
Chen R;Hui L;Sturm RM;Li L
通讯作者:
Li L
影响因子:
30.3
作者:
Attia, Ahmed S.;Schroeder, Kaitlin A.;Skaar, Eric P.
通讯作者:
Skaar, Eric P.
DOI:
10.1074/mcp.m113.034769
发表时间:
2014-01
期刊:
Molecular & cellular proteomics : MCP
影响因子:
--
作者:
Hebert AS;Richards AL;Bailey DJ;Ulbrich A;Coughlin EE;Westphall MS;Coon JJ
通讯作者:
Coon JJ
DOI:
10.1007/s13361-010-0013-8
发表时间:
2011-01
影响因子:
3.2
作者:
Grove, Kerri J.;Frappier, Sara L.;Caprioli, Richard M.
通讯作者:
Caprioli, Richard M.
影响因子:
48
作者:
Andersson, Malin;Groseclose, M. Reid;Caprioli, Richard M.
通讯作者:
Caprioli, Richard M.