Exposure to PM2.5 and PM10 and COVID-19 infection rates and mortality: A one-year observational study in Poland.

Exposure to PM2.5 and PM10 and COVID-19 infection rates and mortality: A one-year observational study in Poland.
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DOI:
10.1016/j.bj.2021.11.006
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发表时间:
2021-12
期刊:
影响因子:
5.5
通讯作者:
Piwowar A
Piwowar A
中科院分区:
医学2区
文献类型:
--
作者:
Czwojdzińska M;Terpińska M;Kuźniarski A;Płaczkowska S;Piwowar A

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大气污染,特别是颗粒物(PM),可能与呼吸衰竭相关的病毒感染有关。文献数据表明,全球SARS-CoV-2感染的强度可能与PM污染水平有关。该研究的目的是在为期一年的观察研究中检查大气污染(以PM2.5和PM10水平衡量)与波兰COVID-19病例和相关死亡人数之间的关系。波兰COVID-19事件和相关死亡的数量和地理分布,以及PM2. 5和PM10暴露水平均来自可公开访问的数据库。计算了各省这些参数的月平均值。对2020年3月至2021年2月期间进行了多元回归分析,考虑了PM2. 5和PM10的平均每月暴露量、每100,000名居民的每月COVID-19发病率和死亡率以及波兰各省的人口密度。仅2020年12月,新增感染人数与三个分析因素显著相关:PM2. 5、人口密度和实验室COVID-19检测次数(R2 = 0. 882)。对于COVID-19死亡率,仅在2020年11月(R2 = 0. 468)获得了具有所有三个显著因素(PM10、人口密度和检测次数)的模型。波兰各地COVID-19事件的分布与各省的年度颗粒物浓度水平无关。仅在某些月份,不同省份的PM2. 5和PM10暴露与COVID-19发病率和死亡率相关。其他辅助因素,如人口密度和进行COVID-19检测的次数,也仅在某些月份与COVID-19相关的感染和死亡相对应。颗粒物不应被视为COVID-19大流行的传播和严重程度的唯一决定因素,但不应忘记其在传染病发病率中的重要性。
Atmospheric contamination, especially particulate matter (PM), can be associated viral infections connected with respiratory failure. Literature data indicates that intensity of SARS-CoV-2 infections worldwide can be associated with PM pollution levels. The aim of the study was to examine the relationship between atmospheric contamination, measured as PM2.5 and PM10 levels, and the number of COVID-19 cases and related deaths in Poland in a one-year observation study. Number and geographical distribution of COVID-19 incidents and related deaths, as well as PM2.5 and PM10 exposure levels in Poland were obtained from publicly accessible databases. Average monthly values of these parameters for individual provinces were calculated. Multiple regression analysis was performed for the period between March 2020 and February 2021, taking into account average monthly exposure to PM2.5 and PM10, monthly COVID-19 incidence and mortality rates per 100,000 inhabitants and the population density across Polish provinces. Only December 2020 the number of new infections was significantly related to the three analyzed factors: PM2.5, population density and the number of laboratory COVID-19 tests (R2 = 0.882). For COVID-19 mortality, a model with all three significant factors: PM10, population density and number of tests was obtained as significant only in November 2020 (R2 = 0.468). The distribution of COVID-19 incidents across Poland was independent from annual levels of particulate matter concentration in provinces. Exposure to PM2.5 and PM10 was associated with COVID-19 incidence and mortality in different provinces only in certain months. Other cofactors such as population density and the number of performed COVID-19 tests also corresponded with both COVID-19-related infections and deaths only in certain months. Particulate matter should not be treated as the sole determinant of the spread and severity of the COVID-19 pandemic but its importance in the incidence of infectious diseases should not be forgotten.
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发表时间: 2020-12-11
影响因子: --
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影响因子: 4
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DOI: 10.1093/infdis/156.3.442
发表时间: 1987-09-01
影响因子: 6.4
作者:
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