Graphene-based materials for tissue engineering.

Graphene-based materials for tissue engineering.
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DOI:
10.1016/j.addr.2016.03.007
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发表时间:
2016-10-01
影响因子:
16.1
通讯作者:
Khademhosseini, Ali
Khademhosseini, Ali
中科院分区:
医学1区
文献类型:
--
作者:
Shin, Su Ryon;Li, Yi-Chen;Jang, Hae Lin;Khoshakhlagh, Parastoo;Akbari, Mohsen;Nasajpour, Amir;Zhang, Yu Shrike;Tamayol, Ali;Khademhosseini, Ali

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石墨烯及其化学衍生物是一类关键的新型纳米材料和量子行为的模型系统。该材料优异的导电性、生物相容性、表面积和热性能引起了科学界的极大兴趣。二维石墨烯材料已广泛应用于生物电子学、成像、药物输送、组织工程等各种生物医学研究领域。在这篇综述中,我们将重点介绍石墨烯基材料在组织工程和再生医学中的最新应用。我们将特别讨论石墨烯基材料在心脏、神经、骨骼、软骨、骨骼肌和皮肤/脂肪组织工程中的应用。我们还讨论了组织工程中石墨烯基材料的潜在风险因素。此外,我们将概述石墨烯基材料在临床应用中的使用机会。
Graphene and its chemical derivatives have been a pivotal new class of nanomaterials and a model system for quantum behavior. The material's excellent electrical conductivity, biocompatibility, surface area and thermal properties are of much interest to the scientific community. Two dimensional graphene materials have been widely used in various biomedical research areas such as bioelectronics, imaging, drug delivery, and tissue engineering. In this review we will highlight the recent applications of graphene-based materials in tissue engineering and regenerative medicine. In particular, we will discuss the application of graphene-based materials in cardiac, neural, bone, cartilage, skeletal muscle, and skin/adipose tissue engineering. We also discuss the potential risk factors of graphene-based materials in tissue engineering. In addition, we will outline the opportunities in the usage of graphene-based materials for clinical applications.
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