Trends in esophageal adenocarcinoma incidence and mortality.
Trends in esophageal adenocarcinoma incidence and mortality.
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DOI：
10.1002/cncr.27834
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发表时间：
2013-03-15
期刊：
影响因子：
6.2
通讯作者：
Feuer, Eric J.
中科院分区：
文献类型：
--
作者：
Hur, Chin;Miller, Melecia;Kong, Chung Yin;Dowling, Emily C.;Nattinger, Kevin J.;Dunn, Michelle;Feuer, Eric J.
在过去的几十年里，食管腺癌（EAC）的发病率迅速上升。本分析的目的是研究美国人群中EAC发病率和死亡率的时间趋势，此外，探讨人群亚组中的这些趋势。美国国家癌症研究所（NCI）监测、流行病学和最终结果（SEER 9）数据用于检查1975年至2009年EAC的发病率和基于发病率（IB）的死亡率。使用NCI的Joinpoint回归程序进一步描述了按癌症分期、性别和种族划分的发病率和IB死亡率的长期趋势。根据SEER 9数据，EAC发病率和IB死亡率在美国持续上升。然而，自1990年代中期以来，EAC发病率和IB死亡率的总体增长率似乎正在放缓。此外，在早期癌症中，从1990年代末开始，IB死亡率明显趋于平稳，发病率也出现了差异。在研究期间，男性的年平均发病率增长率为6.1%，女性为5.9%。在美国，EAC发病率和IB死亡率继续上升，尽管近年来的速度有所放缓。在早期癌症中，IB死亡率和发病率存在分歧，主要是因为IB死亡率从1990年代末开始趋于稳定。尽管EAC在女性中仍然不太常见，但男女EAC发病率的增长率相似。
Over the past several decades, the incidence of esophageal adenocarcinoma (EAC) has rapidly increased. The purpose of this analysis was to examine temporal trends in EAC incidence and mortality within the US population and, in addition, to explore these trends within subgroups of the population. The National Cancer Institute (NCI) Surveillance, Epidemiology and End Results (SEER 9) data were used to examine incidence and incidence-based (IB) mortality in EAC from 1975 to 2009. Secular trends in incidence and IB mortality by cancer stage, sex, and race were further characterized using the NCI's Joinpoint Regression program. Based on SEER 9 data, EAC incidence and IB mortality continues to increase in the United States. However, since the mid-1990s, the overall rate of increase in both EAC incidence and IB mortality appears to be slowing. In addition, in early-stage cancers, there is a noticeable leveling off of IB mortality rates and divergence from incidence starting in the late 1990s. Over the study period, the average annual percentage increase in incidence was 6.1% in men and 5.9% in women. EAC incidence and IB mortality rates continue to rise in the United States, although at a slower rate in more recent years. In early-stage cancers, IB mortality and incidence rates have diverged primarily because IB mortality rates have plateaued beginning in the late 1990s. Although EAC continues to be less common in women, the rate of increase in EAC incidence is similar in both sexes.
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影响因子：
29.4
作者：
Spechler SJ;Sharma P;Souza RF;Inadomi JM;Shaheen NJ;American Gastroenterological Association
通讯作者：
American Gastroenterological Association
影响因子：
7.2
作者：
CHU, KC;MILLER, BA;HANKEY, BF
通讯作者：
HANKEY, BF
影响因子：
1.9
作者：
Nordenstedt, Helena;El-Serag, Hashem
通讯作者：
El-Serag, Hashem
DOI：
10.1093/jnci/djn211
发表时间：
2008-08-20
期刊：
Journal of the National Cancer Institute
影响因子：
--
作者：
Brown LM;Devesa SS;Chow WH
通讯作者：
Chow WH
影响因子：
6.4
作者：
Polednak, AP
通讯作者：
Polednak, AP