Spatial and memory circuits in the medial entorhinal cortex.
Spatial and memory circuits in the medial entorhinal cortex.
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DOI:
10.1016/j.conb.2014.10.008
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发表时间:
2015-06
影响因子:
5.7
通讯作者:
Leutgeb JK
中科院分区:
文献类型:
--
作者:
Sasaki T;Leutgeb S;Leutgeb JK
The large capacity of episodic memory is thought to be supported by the emergence of distinct hippocampal cell assemblies for unrelated memories, such that interference is minimized. In large-scale population recordings, the orthogonal nature of hippocampal representations across environments is evident in the complete reorganization of the firing locations of hippocampal place cells. Entorhinal grid cells provide inputs to the hippocampus, and their firing patterns shift relative to each other across different environments. Although this suggests that altered grid cell firing could generate distinct hippocampal population codes, it has recently been shown that new and distinct hippocampal place fields emerge while grid cell firing is compromised. We therefore propose that separate circuits within the medial entorhinal cortex are specialized for performing either spatial or memory-related computations.
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影响因子:
16.2
作者:
Brandon MP;Koenig J;Leutgeb JK;Leutgeb S
通讯作者:
Leutgeb S
DOI:
10.1523/jneurosci.1433-11.2011
发表时间:
2011-06-22
期刊:
The Journal of neuroscience : the official journal of the Society for Neuroscience
影响因子:
--
作者:
Monaco JD;Abbott LF
通讯作者:
Abbott LF
影响因子:
25
作者:
Bonnevie, Tora;Dunn, Benjamin;Moser, May-Britt
通讯作者:
Moser, May-Britt
影响因子:
56.9
作者:
Koenig, Julie;Linder, Ashley N.;Leutgeb, Stefan
通讯作者:
Leutgeb, Stefan
影响因子:
16.2
作者:
Bjerknes, Tale L.;Moser, Edvard I.;Moser, May-Britt
通讯作者:
Moser, May-Britt