The impact of threat of shock-induced anxiety on memory encoding and retrieval.
The impact of threat of shock-induced anxiety on memory encoding and retrieval.
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DOI：
10.1101/lm.045187.117
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发表时间：
2017-10
期刊：
影响因子：
--
通讯作者：
Robinson OJ
中科院分区：
文献类型：
--
作者：
Bolton S;Robinson OJ
焦虑症是最常见的精神健康障碍，每天短暂的焦虑感（或“压力”）无处不在。然而，短暂性和病理性焦虑对高阶认知功能（包括短期和长期记忆）的确切影响尚不清楚。更清晰地理解焦虑-记忆的关系是很重要的，因为焦虑的核心症状之一，在创伤后应激障碍（PTSD）中最为突出，是以生动记忆的形式侵入性地重新体验创伤事件。因此，本研究旨在探讨诱发焦虑（休克威胁）对记忆编码和检索的影响。86名健康参与者完成了评估任务：视觉空间工作记忆、言语识别、面部识别和联想记忆。关键的是，焦虑在受试者内部被操纵：在电击威胁和安全（无电击）条件下，信息被编码和检索。结果显示，在威胁条件下对信息进行编码并随后进行检索，视觉空间工作记忆得到增强，而无论在何种条件下进行检索，威胁都会损害对面孔的编码。然而，情景记忆和言语短期识别没有受损。这些发现表明，健康个体的短暂焦虑对记忆的影响是特定领域的，而不是一般领域的。未来的研究将受益于将这些发现扩展到焦虑症患者，以描绘适应性反应和不适应反应之间的差异。
Anxiety disorders are the most common mental health disorders, and daily transient feelings of anxiety (or “stress”) are ubiquitous. However, the precise impact of both transient and pathological anxiety on higher-order cognitive functions, including short- and long-term memory, is poorly understood. A clearer understanding of the anxiety–memory relationship is important as one of the core symptoms of anxiety, most prominently in post-traumatic stress disorder (PTSD), is intrusive reexperiencing of traumatic events in the form of vivid memories. This study therefore aimed to examine the impact of induced anxiety (threat of shock) on memory encoding and retrieval. Eighty-six healthy participants completed tasks assessing: visuospatial working memory, verbal recognition, face recognition, and associative memory. Critically, anxiety was manipulated within-subjects: information was both encoded and retrieved under threat of shock and safe (no shock) conditions. Results revealed that visuospatial working memory was enhanced when information was encoded and subsequently retrieved under threat, and that threat impaired the encoding of faces regardless of the condition in which it was retrieved. Episodic memory and verbal short-term recognition were, however, unimpaired. These findings indicate that transient anxiety in healthy individuals has domain-specific, rather than domain-general, impacts on memory. Future studies would benefit from expanding these findings into anxiety disorder patients to delineate the differences between adaptive and maladaptive responding.
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DOI：
10.1101/lm.032409.113
发表时间：
2013-12-17
期刊：
Learning & memory (Cold Spring Harbor, N.Y.)
影响因子：
--
作者：
Bisby JA;Burgess N
通讯作者：
Burgess N
影响因子：
2.1
作者：
Jaeggi, Susanne M.;Buschkuehl, Martin;Meier, Beat
通讯作者：
Meier, Beat
影响因子：
64.8
作者：
Collins, Pamela Y.;Patel, Vikram;Joestl, Sarah S.;March, Dana;Insel, Thomas R.;Daar, Abdallah S.
通讯作者：
Daar, Abdallah S.
DOI：
10.1192/bjp.bp.110.090217
发表时间：
2011-09
期刊：
The British journal of psychiatry : the journal of mental science
影响因子：
--
作者：
Butters MA;Bhalla RK;Andreescu C;Wetherell JL;Mantella R;Begley AE;Lenze EJ
通讯作者：
Lenze EJ
影响因子：
2.9
作者：
Attwood AS;Catling JC;Kwong AS;Munafò MR
通讯作者：
Munafò MR