Emergence of methicillin-resistant Staphylococcus aureus of animal origin in humans.

Emergence of methicillin-resistant Staphylococcus aureus of animal origin in humans.
复制标题

DOI:
10.3201/eid1312.070384
复制
发表时间:
2007-12
影响因子:
11.8
通讯作者:
Kluytmans J
Kluytmans J
中科院分区:
医学2区
文献类型:
--
作者:
van Loo I;Huijsdens X;Tiemersma E;de Neeling A;van de Sande-Bruinsma N;Beaujean D;Voss A;Kluytmans J

文献摘要

参考文献

被引文献

相似文献

来自动物宿主的 MRSA 最近已进入人类群体,目前占荷兰所有 MRSA 的 20% 以上。 2003 年,荷兰出现了一种新的耐甲氧西林金黄色葡萄球菌 (MRSA) 菌株,该菌株无法通过 Sma1 脉冲场凝胶电泳 (NT-MRSA) 进行分型。研究人员对人类中的 NT-MRSA 与动物中的储存库之间的关系进行了研究。 2006年7月加强监测后,NT-MRSA的发生率从2002年的0%上升到>21%。从地理上看,NT-MRSA主要集中在养猪业。一项病例对照研究表明,NT-MRSA 携带者通常是养猪户或养牛户(养猪户比值比 [OR] 12.2,95% 置信区间 [CI] 3.1–48.6;养牛户 OR 19.7,95% CI 2.3–169.5)。分子分型显示 NT-MRSA 菌株属于一种新的克隆复合体 ST 398。这项研究表明,来自动物宿主的 MRSA 最近已进入人类群体,目前占荷兰所有 MRSA 的 20% 以上。
MRSA from an animal reservoir has recently entered the human population and is now responsible for >20% of all MRSA in the Netherlands. In 2003 in the Netherlands, a new methicillin-resistant Staphylococcus aureus (MRSA) strain emerged that could not be typed with Sma1 pulsed-field gel electrophoresis (NT-MRSA). The association of NT-MRSA in humans with a reservoir in animals was investigated. The frequency of NT-MRSA increased from 0% in 2002 to >21% after intensified surveillance was implemented in July 2006. Geographically, NT-MRSA clustered with pig farming. A case–control study showed that carriers of NT-MRSA were more often pig or cattle farmers (pig farmers odds ratio [OR] 12.2, 95% confidence interval [CI] 3.1–48.6; cattle farmers OR 19.7, 95% CI 2.3–169.5). Molecular typing showed that the NT-MRSA strains belonged to a new clonal complex, ST 398. This study shows that MRSA from an animal reservoir has recently entered the human population and is now responsible for >20% of all MRSA in the Netherlands.
DOI: 10.1016/j.vetmic.2007.01.027
发表时间: 2007-06-21
影响因子: 3.3
作者:
de Neeling, A. J.;van den Broek, M. J. M.;Huijsdens, X. W.
通讯作者: Huijsdens, X. W.
DOI: 10.3201/eid1103.040481
发表时间: 2005-03-01
影响因子: 11.8
作者:
Weese, JS;Archambault, M;Low, DE
通讯作者: Low, DE
DOI: 10.1128/jcm.42.7.3077-3082.2004
发表时间: 2004-07-01
影响因子: 9.4
作者:
Wannet, WJB;Spalburg, E;de Neeling, AJ
通讯作者: de Neeling, AJ
DOI: 10.1111/j.1469-0691.2006.01341.x
发表时间: 2006-03-01
影响因子: 14.2
作者:
Kluytmans-VandenBergh, MFQ;Kluytmans, JAJW
通讯作者: Kluytmans, JAJW
DOI: 10.3201/eid1105.040866
发表时间: 2005-05
影响因子: 11.8
作者:
Armand-Lefevre L;Ruimy R;Andremont A
通讯作者: Andremont A