COVID-19 in pediatric patients undergoing chronic dialysis and kidney transplantation.
COVID-19 in pediatric patients undergoing chronic dialysis and kidney transplantation.
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DOI：
10.1007/s00431-021-04191-z
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发表时间：
2022-01
影响因子：
3.6
通讯作者：
Alpay H
中科院分区：
文献类型：
--
作者：
Canpolat N;Yıldırım ZY;Yıldız N;Taşdemir M;Göknar N;Evrengül H;Gülmez R;Aksu B;Dursun H;Özçelik G;Yavaşcan Ö;Çiçek RY;Tülpar S;Hacıhamdioğlu DÖ;Nayır A;Alpay H
该研究旨在介绍接受肾脏替代治疗 (RRT) 的儿科患者中 COVID-19 的发病率，并比较透析组和肾移植组 (KTx) 之间疾病的严重程度和结果。这项多中心观察性研究于 2020 年 4 月 1 日至 12 月 31 日在伊斯坦布尔进行。土耳其儿科肾病协会伊斯坦布尔分会的成员被要求报告所有接受 RRT 的 COVID-19 确诊病例，以及 20 岁以下流行的 RRT 患者人数。 12 个中心共报告了 46 例 COVID-19 确诊病例，其中 17 例是透析患者，29 例是 KTx 接受者。因此，在伊斯坦布尔的 9 个月期间，透析患者和 KTx 接受者中的 COVID-19 发病率为 9.3% 和 9.2%。 12 名 KTx 接受者和 3 名透析患者没有症状（p = 0.12）。透析组和 KTx 组中大多数有症状的患者患有轻度呼吸道疾病。只有两名患者（每组一名）经历了严重的病程，并且只有一名血液透析患者病情危重，需要机械通气。在整个队列中，一名患有多种合并症的血液透析患者死亡。结论：虽然大多数病例无症状或病程较轻，但接受透析和肾移植的儿科患者感染 COVID-19 的风险增加。
The study aims to present the incidence of COVID-19 in pediatric patients undergoing renal replacement therapy (RRT) and to compare the severity and outcomes of the disease between the dialysis and kidney transplant (KTx) groups. This multicenter observational study was conducted between 1 April and 31 December 2020 in Istanbul. Members of the Istanbul branch of the Turkish Pediatric Nephrology Association were asked to report all confirmed cases of COVID-19 who were on RRT, as well as the number of prevalent RRT patients under the age of 20. A total of 46 confirmed cases of COVID-19 were reported from 12 centers, of which 17 were dialysis patients, and 29 were KTx recipients. Thus, the incidence rate of COVID-19 was 9.3% among dialysis patients and 9.2% among KTx recipients over a 9-month period in Istanbul. Twelve KTx recipients and three dialysis patients were asymptomatic (p = 0.12). Most of the symptomatic patients in both the dialysis and KTx groups had a mild respiratory illness. Only two patients, one in each group, experienced a severe disease course, and only one hemodialysis patient had a critical illness that required mechanical ventilation. In the entire cohort, one hemodialysis patient with multiple comorbidities died. Conclusion: While most cases are asymptomatic or have a mild disease course, pediatric patients undergoing dialysis and a kidney transplant are at increased risk for COVID-19.
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DOI：
10.1186/cc11454
发表时间：
2013-02-04
期刊：
Critical care (London, England)
影响因子：
--
作者：
Kellum JA;Lameire N;KDIGO AKI Guideline Work Group
通讯作者：
KDIGO AKI Guideline Work Group
影响因子：
0.9
作者：
Lum E;Bunnapradist S;Multani A;Beaird OE;Carlson M;Gaynor P;Kotton C;Abdalla B;Danovitch G;Kendrick E;Nieves-Borrero K;Pham PT;Yabu J;Schaenman J
通讯作者：
Schaenman J
影响因子：
36.4
作者：
Goetzinger, Florian;Santiago-Garcia, Begona;Tebruegge, Marc
通讯作者：
Tebruegge, Marc
影响因子：
3
作者：
Melgosa, M.;Madrid, A.;Perez-Beltran, V
通讯作者：
Perez-Beltran, V
影响因子：
8.8
作者：
Bossini, Nicola;Alberici, Federico;Scolari, Francesco
通讯作者：
Scolari, Francesco