Prevalence of dry eye syndrome and diabetic retinopathy in type 2 diabetic patients.
Prevalence of dry eye syndrome and diabetic retinopathy in type 2 diabetic patients.
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DOI：
10.1186/1471-2415-8-10
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发表时间：
2008-06-02
影响因子：
2
通讯作者：
Shoja MR
中科院分区：
文献类型：
--
作者：
Manaviat MR;Rashidi M;Afkhami-Ardekani M;Shoja MR
本研究旨在评估 2 型糖尿病患者干眼综合征和糖尿病视网膜病变 (DR) 的患病率及其影响因素。连续选择了转诊至 Yazd 糖尿病研究中心的 199 名 2 型糖尿病患者。所有受试者均通过有关其他疾病和药物的调查问卷进行评估。通过泪膜破裂时间测试和泪液分泌测试来评估干眼症。所有受试者均接受间接检眼镜检查和视网膜彩色摄影。 DR 根据早期治疗糖尿病视网膜病变 (ETDRS) 标准进行分级。在 199 名受试者中，108 名患者（54.3%）患有干眼综合症。尽管干眼症在老年和女性患者中更为常见，但这种关联并不显着。但干眼综合征与糖尿病病程之间存在显着相关性（P = 0.01）。患有 DR 的糖尿病患者更容易出现干眼综合征（P = 0.02）。 140例（70.35%）患者出现DR，其中轻度非增殖性DR（NPDR）34例（17.1%），中度NPDR 34例（17.1%），重度NPDR 22例（11.1%），增殖性DR（PDR）25例（25.1%）。年龄、性别、糖尿病病程与DR之间存在显着相关性。在这项研究中，干眼综合症的患病率为 54.3%。糖尿病和干眼症似乎有共同的关联。需要进行进一步的研究以确定病因关系。然而，干眼检查应该是评估糖尿病眼病的一个组成部分。
This study was performed to assess the prevalence of dry eye syndrome and diabetic retinopathy (DR) in type 2 diabetic patients and their contributing factors. 199 type 2 diabetic patients referred to Yazd Diabetes Research Center were consecutively selected. All Subjects were assessed by questionnaire about other diseases and drugs. Dry eye syndrome was assessed with Tear break up time tests and Schirmer. All the subjects underwent indirect ophthalmoscopy and retinal color photography. DR was graded according to early Treatment Diabetic Retinopathy (ETDRS) criteria. Of 199 subjects, 108 patients (54.3%) suffer from dry eye syndrome. Although dry eye syndrome was more common in older and female patients, this association was not significant. But there was significantly association between dry eye syndrome and duration of diabetes (P = 0.01). Dry eye syndrome was more frequent in diabetic patients with DR (P = 0.02). DR was found in 140 patients (70.35%), which included 34 patients (17.1%) with mild non proliferative DR (NPDR), 34 patients (17.1%) with moderate NPDR, 22 patients (11.1%) with severe NPDR and 25 patients (25.1%) with proliferative DR (PDR). There were significant relation between age, sex and duration of diabetes and DR. In this study the prevalence of dry eye syndrome was 54.3%. Diabetes and dry eyes appear to have a common association. Further studies need to be undertaken to establish an etiologic relationship. However, examination for dry eye should be an integral part of the assessment of diabetic eye disease.
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影响因子：
4.1
作者：
Cahill, M;Halley, A;Acheson, RW
通讯作者：
Acheson, RW
影响因子：
3.5
作者：
SEGATO, T;MIDENA, E;CREPALDI, G
通讯作者：
CREPALDI, G
影响因子：
4.1
作者：
Goebbels, M
通讯作者：
Goebbels, M
影响因子：
4.4
作者：
Rema, M;Premkumar, S;Mohan, V
通讯作者：
Mohan, V
影响因子：
--
作者：
KLEIN, R;KLEIN, BEK;DEMETS, DL
通讯作者：
DEMETS, DL