Multiple types of Ca2+ channels in visceral smooth muscle cells.
Multiple types of Ca2+ channels in visceral smooth muscle cells.
复制标题
内脏平滑肌细胞中多种类型的 Ca2 通道。
DOI:
10.1007/bf00370463
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发表时间:
1991
期刊:
影响因子:
--
通讯作者:
WalshJr,JV
中科院分区:
文献类型:
--
作者:
Vivaudou,MB;Singer,JJ;WalshJr,JV
Single-channel currents were recorded from two classes of Ca2+channels in visceral smooth muscle cells isolated from the stomach of the toad,Bufo marinus: a class of small-conductance channels (approximately 11 pS) and a class of large-conductance channels (approximately 26 pS). Small-conductance channels were present in a majority of patches and gave rise to a slowly inactivating current (t1/2≈ 250 ms at 0 mV). Openings of large-conductance channels could be unequivocally resolved only in the presence of the dihydropyridine Ca2+agonist Bay K 8644. Two subtypes of the large-conductance channels were found — those with a very slow rate of decay (> 500 ms) and those with a faster one (< 100ms). Large-conductance channels resemble L-type Ca2+channels of other preparations. Small-conductance channels do not fit unambiguously into the other existing categories (i.e., N or T). Correspondence between single-channel and macroscopic Ca2+currents is discussed.
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影响因子:
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通讯作者:
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作者:
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DOI:
10.1016/s0140-6736(76)92592-7
发表时间:
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期刊:
The Lancet
影响因子:
--
作者:
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通讯作者:
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DOI:
10.1111/j.1524-4725.1985.tb02891.x
发表时间:
1985
期刊:
The Journal of dermatologic surgery and oncology
影响因子:
--
作者:
D. Ellis;R. Wheeland;H. Solomon
通讯作者:
H. Solomon