Computational cardiology: the bidomain based modified Hill model incorporating viscous effects for cardiac defibrillation
Computational cardiology: the bidomain based modified Hill model incorporating viscous effects for cardiac defibrillation
复制标题
计算心脏病学：基于双域的改良希尔模型，结合粘性效应用于心脏除颤
DOI：
10.1007/s00466-017-1495-z
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发表时间：
2018
影响因子：
4.1
通讯作者：
Kaliske M.
中科院分区：
文献类型：
--
作者：
Cansiz;Kaliske M.
由于实验设施有限，心脏除颤的工作机制仍存在争议，三分之一的患者甚至对心脏再同步治疗没有反应。为了在实现除颤现象的未揭示机制方面取得一个里程碑，我们提出了一种基于双域的心脏机电有限元公式，考虑了许多研究人员忽视的粘性效应。为此，该材料被视为电粘活性材料，并通过修改后的 Hill 模型进行描述（Cansız 等人，ComputMethodsApplMechEng 315:434–466, 2017）。在数值方面，我们采用交错求解方法，其中双域方程的椭圆形和抛物线部分以及机械场依次求解。比较模拟表明，粘弹性和弹性配方在向心肌组织施加外部电场时会导致显着不同的结果。此外，与单片方案相比，所实现的框架需要显着更少的计算时间和内存，而不会损失所提供示例的稳定性。
Working mechanisms of the cardiac defibrillation are still in debate due to the limited experimental facilities and one-third of patients even do not respond to cardiac resynchronization therapy. With an aim to develop a milestone towards reaching the unrevealed mechanisms of the defibrillation phenomenon, we propose a bidomain based finite element formulation of cardiac electromechanics by taking into account the viscous effects that are disregarded by many researchers. To do so, the material is deemed as an electro-visco-active material and described by the modified Hill model (Cansız et al. in Comput Methods Appl Mech Eng 315:434–466, 2017). On the numerical side, we utilize a staggered solution method, where the elliptic and parabolic part of the bidomain equations and the mechanical field are solved sequentially. The comparative simulations designate that the viscoelastic and elastic formulations lead to remarkably different outcomes upon an externally applied electric field to the myocardial tissue. Besides, the achieved framework requires significantly less computational time and memory compared to monolithic schemes without loss of stability for the presented examples.
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DOI：
--
发表时间：
2013
期刊：
Computers in cardiology
影响因子：
--
作者：
Jean Bragard;J. Elorza;E. Cherry;F. Fenton
通讯作者：
F. Fenton
医学诊断错误的发生率。
影响因子：
5.4
作者：
Graber ML
通讯作者：
Graber ML
DOI：
10.1109/tbme.2009.2022548
发表时间：
2009-10
期刊：
IEEE transactions on bio-medical engineering
影响因子：
--
作者：
Southern JA;Plank G;Vigmond EJ;Whiteley JP
通讯作者：
Whiteley JP
DOI：
10.1080/10255842.2014.881475
发表时间：
2015-08-18
影响因子：
1.6
作者：
Cansiz, F. Baris Can;Dal, Huesnue;Kaliske, Michael
通讯作者：
Kaliske, Michael
影响因子：
--
作者：
A. Pollard;N. Hooke;C. Henriquez
通讯作者：
A. Pollard;N. Hooke;C. Henriquez