Nanoscale live-cell imaging using hopping probe ion conductance microscopy.
Nanoscale live-cell imaging using hopping probe ion conductance microscopy.
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DOI:
10.1038/nmeth.1306
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发表时间:
2009-04
期刊:
影响因子:
48
通讯作者:
Korchev, Yuri E.
中科院分区:
文献类型:
--
作者:
Novak, Pavel;Li, Chao;Shevchuk, Andrew I.;Stepanyan, Ruben;Caldwell, Matthew;Hughes, Simon;Smart, Trevor G.;Gorelik, Julia;Ostanin, Victor P.;Lab, Max J.;Moss, Guy W. J.;Frolenkov, Gregory I.;Klenerman, David;Korchev, Yuri E.
We describe a major advance in scanning ion conductance microscopy: a new hopping mode that allows non-contact imaging of the complex surfaces of live cells with resolution better than 20 nm. The effectiveness of this novel technique was demonstrated by imaging networks of cultured rat hippocampal neurons and mechanosensory stereocilia of mouse cochlear hair cells. The technique allows studying nanoscale phenomena on the surface of live cells under physiological conditions.
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影响因子:
21.3
作者:
Korchev, YE;Negulyaev, YA;Lab, MJ
通讯作者:
Lab, MJ
DOI:
10.1046/j.1365-2818.2003.01248.x
发表时间:
2003-11-01
期刊:
JOURNAL OF MICROSCOPY-OXFORD
影响因子:
--
作者:
Happel, P;Hoffmann, G;Dietzel, ID
通讯作者:
Dietzel, ID
影响因子:
3.4
作者:
Langer, MG;Fink, S;Ruppersberg, JP
通讯作者:
Ruppersberg, JP
影响因子:
2.2
作者:
Langer, MG;Koitschev, A;Ruppersberg, JP
通讯作者:
Ruppersberg, JP
影响因子:
3
作者:
Mann, SA;Hoffmann, G;Dietzel, ID
通讯作者:
Dietzel, ID