Standardizing evaluation of pQCT image quality in the presence of subject movement: qualitative versus quantitative assessment.
Standardizing evaluation of pQCT image quality in the presence of subject movement: qualitative versus quantitative assessment.
复制标题
在受试者运动的存在下对PQCT图像质量的标准化评估：定性与定量评估。
DOI：
10.1007/s00223-013-9803-x
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发表时间：
2014-02
影响因子：
4.2
通讯作者：
Going, Scott B.
中科院分区：
文献类型：
--
作者：
Blew, Robert M.;Lee, Vinson R.;Farr, Joshua N.;Schiferl, Daniel J.;Going, Scott B.
关键词：
外周定量计算机断层扫描（pQCT）是评估四肢骨骼参数的重要工具，但受试者运动及其对图像质量的影响仍然是一个挑战。目前确定图像活力的方法是通过目视检查，但pQCT缺乏定量评价。因此，本研究的目的是（1）检查定性视觉检查量表的可靠性，（2）建立定量运动评估方法。对506名健康女孩（9- 13岁）的股骨和胫骨干区域进行扫描。由三名技术人员使用线性标称量表独立评定扫描的运动。量化，运动与肢体大小的比率（%移动）提供了运动伪影的测量。检查重复扫描子样本（n=46），以确定%移动对骨参数的影响。测量者之间的一致性很强（胫骨ICC = 0.732，股骨ICC = 0.812），但在3级或4级扫描中观察到更大的变异性，即重复或不重复之间的界限。定量方法发现≥95%的受试者的%Move <25%。初始运动高于和低于25%的组的初始和重复扫描的比较显示，在>25%的组中存在显著差异。pQCT目视检查量表可以是图像质量的可靠度量，但技术人员可能会周期性地错误表征受试者运动。所提出的定量方法产生更一致的运动评估，并可以统一跨实验室的程序。数据表明，25%的运动划定，以确定骨干扫描是可行的，还是需要重复。
Peripheral quantitative computed tomography (pQCT) is an essential tool for assessing bone parameters of the limbs, but subject movement and its impact on image quality remains a challenge to manage. The current approach to determine image viability is by visual inspection, but pQCT lacks a quantitative evaluation. Therefore, the aims of this study were to (1) examine the reliability of a qualitative visual inspection scale, and (2) establish a quantitative motion assessment methodology. Scans were performed on 506 healthy girls (9–13yr) at diaphyseal regions of the femur and tibia. Scans were rated for movement independently by three technicians using a linear, nominal scale. Quantitatively, a ratio of movement to limb size (%Move) provided a measure of movement artifact. A repeat-scan subsample (n=46) was examined to determine %Move’s impact on bone parameters. Agreement between measurers was strong (ICC = .732 for tibia, .812 for femur), but greater variability was observed in scans rated 3 or 4, the delineation between repeat or no repeat. The quantitative approach found ≥95% of subjects had %Move <25%. Comparison of initial and repeat scans by groups above and below 25% initial movement, showed significant differences in the >25% grouping. A pQCT visual inspection scale can be a reliable metric of image quality but technicians may periodically mischaracterize subject motion. The presented quantitative methodology yields more consistent movement assessment and could unify procedure across laboratories. Data suggest a delineation of 25% movement for determining whether a diaphyseal scan is viable or requires repeat.
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影响因子：
4.1
作者：
Fung, Ellen B.;Vichinsky, Elliott P.;Zemel, Babette S.
通讯作者：
Zemel, Babette S.
影响因子：
3.2
作者：
Sherk, Vanessa D.;Bemben, Michael G.;Bemben, Debra A.
通讯作者：
Bemben, Debra A.
影响因子：
7.1
作者：
KELLEY, DE;SLASKY, BS;JANOSKY, J
通讯作者：
JANOSKY, J
影响因子：
4.9
作者：
HENDEE, WR;EDWARDS, FM
通讯作者：
EDWARDS, FM
影响因子：
8
作者：
Barlow, Sarah E.
通讯作者：
Barlow, Sarah E.