Detecting cognitive impairment in individuals at risk for cardiovascular disease: the "Clock-in-the-Box" screening test.
Detecting cognitive impairment in individuals at risk for cardiovascular disease: the "Clock-in-the-Box" screening test.
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检测患有心血管疾病风险的个体的认知障碍：“盒子里的筛查”筛查测试。
DOI：
10.1002/gps.2635
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发表时间：
2011-09
影响因子：
4
通讯作者：
McGlinchey, Regina E.
中科院分区：
文献类型：
--
作者：
Grande, Laura J.;Rudolph, James L.;Milberg, William P.;Barber, Colleen E.;McGlinchey, Regina E.
本研究的目的是评估相对于神经心理测试的认知功能筛查方法——盒子时钟（CIB）在有心血管风险的老年人群中的表现。招募了一组有心血管风险的老年患者（50岁至50岁）进行CIB，并完成了一个简短的神经心理学测试，包括Trailmaking测试、Hopkins Verbal Learning Test （HVLT）和流畅性测试。在CIB上的表现根据标准标准（范围0-8,0-最差）进行评分。用神经心理学测量方法比较被试在总CIB、工作记忆分量表（CIB- wm）和计划/组织（COB-PO）方面的表现。研究对象（n=127）年龄较大（67±7岁），女性（n=42）占33%，非白种人（n=53）占42%。心脏危险因素普遍存在：高血压（83%）、高脂血症（74%）、超重（84%）、糖尿病（48%）、既往心脏病（39%）和吸烟（11%）。CIB平均完成时间为84±21秒（平均6.5±1.3），具有良好的量表间信度（κ= 0.809, p< 0.01）。CIB-WM子量表与Trailmaking B和HVLT学习、回忆和识别的表现显著相关。CIB-PO子量表与语义和音位流畅性、Trailmaking B和HVLT学习和回忆显著相关。在回归模型中，CIB-WM显著预测了HVLT学习、回忆和记忆的表现。CIB-PO子量表预测受试者在Trailmaking B、HVLT学习和HVLT回忆方面的表现。CIB是一种简短的认知筛查工具，在心血管危险人群中具有良好的信度和预测效度。CIB-WM和CIB-PO量表可为临床医生提供实用价值。
The purpose of this study was to evaluate the performance on the Clock-in-the-Box (CIB), a screening measure for cognitive function, relative to neuropsychological testing in an older population with cardiovascular risk. A prospective cohort of older patients (>50 years) with cardiovascular risk were recruited to perform the CIB and complete a brief neuropsychological battery consisting of Trailmaking tests, the Hopkins Verbal Learning Test (HVLT), and fluency tasks. Performance on the CIB was scored according to standard criteria (range 0-8, 0-worst). The performance on the total CIB, working memory subscale (CIB-WM), and planning/ organization (COB-PO) were compared to neuropsychological measures. The cohort (n=127) was older (age 67±7 years) and diverse with 33% female (n=42) and 42% non-white race (n=53). Cardiac risk factors were prevalent: hypertension (83%), hyperlipidemia (74%), overweight (84%), diabetes (48%), prior cardiac disease (39%), and smoking (11%). The CIB (mean 6.5±1.3) took 84±21 seconds on average to complete and had good inter-rater reliability (κ=.809, p<.01). The CIB-WM subscale was significantly correlated with performance on Trailmaking B and HVLT learning, recall, and recognition. The CIB-PO subscale was significantly associated with semantic and phonemic fluency, Trailmaking B, and HVLT learning and recall. In regression modeling, CIB-WM significantly predicted performance on HVLT learning, recall, and retention. CIB-PO subscale predicted performance on Trailmaking B, HVLT learning, and HVLT recall. The CIB is a brief cognitive screening instrument with good reliability and predictive validity in a CV risk population. The CIB-WM and CIB-PO subscales could provide utility for clinicians.
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影响因子：
11
作者：
O'Sullivan, M;Morris, RG;Markus, HS
通讯作者：
Markus, HS
DOI：
10.1017/s1355617702860027
发表时间：
2002-09-01
影响因子：
2.6
作者：
Cohen, RA;Paul, RH;Gordon, N
通讯作者：
Gordon, N
影响因子：
2.5
作者：
Stübner, S;Schön, T;Hampel, H
通讯作者：
Hampel, H
DOI：
10.1046/j.1532-5415.2003.51463.x
发表时间：
2003-10-01
影响因子：
6.3
作者：
Pugh, KG;Kiely, DK;Lipsitz, LA
通讯作者：
Lipsitz, LA
DOI：
10.1017/s1355617799566034
发表时间：
1999-09-01
影响因子：
2.6
作者：
Cahn-Weiner, DA;Sullivan, EV;Pfefferbaum, A
通讯作者：
Pfefferbaum, A