The Blue Lotus Flower (Nymphea caerulea) Resin Used in a New Type of Electronic Cigarette, the Re-Buildable Dripping Atomizer.

The Blue Lotus Flower (Nymphea caerulea) Resin Used in a New Type of Electronic Cigarette, the Re-Buildable Dripping Atomizer.
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DOI:
10.1080/02791072.2017.1290304
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发表时间:
2017-07
影响因子:
2.8
通讯作者:
Peace MR
Peace MR
中科院分区:
医学4区
文献类型:
--
作者:
Poklis JL;Mulder HA;Halquist MS;Wolf CE;Poklis A;Peace MR

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蓝莲花(Nymphea caerulea)是一种埃及睡莲,含有阿扑吗啡和荷叶碱。阿扑吗啡被描述为一种精神活性生物碱,是一种非选择性多巴胺激动剂,主要用于治疗帕金森病,因为它刺激多巴胺受体并改善运动功能。荷叶碱是一种与多巴胺受体阻滞相关的生物碱。今天,蓝莲花被用作助眠和缓解焦虑。可修复滴落雾化器(RDA)是一种电子香烟,与电子烟液从储存容器芯吸到线圈的典型电子香烟相比,该电子香烟允许将电子烟液直接施加到雾化器中的线圈上以进行雾化。我们的实验室收到了一个深棕色的树脂材料从一个关心的父母。这些树脂是从一名有大麻使用史的青少年身上没收的。该树脂经鉴定为蓝莲花(N. caerulea)。分析了该树脂以及四种市售蓝莲花产品的含量。在两个样品中检测到阿扑吗啡,在所有五个样品中检测到荷叶碱。没收的树脂经测定不含阿扑吗啡和4300 ng/g荷叶碱。荷叶碱树脂显示出使用aRDA电子香烟雾化。
The blue lotus flower (Nymphea caerulea) is an Egyptian water lily containing apomorphine and nuciferine. Apomorphine has been described as a psychoactive alkaloid and is a non-selective dopamine agonist primarily used to treat Parkinson’s disease as it stimulates dopamine receptors and improves motor function. Nuciferine is an alkaloid associated with dopamine receptor blockade. Today, blue lotus flower is used as a sleep aid and anxiety reliever. The rebuildable dripping atomizer (RDA) is an electronic cigarette that allows direct application of an e-liquid onto the coil in the atomizer for aerosolization, compared to a typical electronic cigarette where the e-liquid is wicked from a storage vessel to the coil. Our laboratory received a dark-brown resin material from a concerned parent. The resin had been confiscated from an adolescent who had a reported history of marijuana use. The resin was later identified as blue lotus flower (N. caerulea). This resin, together with four commercially available blue lotus products, was analyzed for content. Apomorphine was detected in two samples, and nuciferine was detected in all five samples. The confiscated resin was determined to contain no apomorphine and 4300 ng/g of nuciferine. The nuciferine resin was shown to aerosolize using aRDA electric cigarette.
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