InAs(ZnCdS) quantum dots optimized for biological imaging in the near-infrared.

InAs(ZnCdS) quantum dots optimized for biological imaging in the near-infrared.
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DOI:
10.1021/ja908250r
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发表时间:
2010-01-20
影响因子:
15
通讯作者:
Bawendi, Moungi G.
Bawendi, Moungi G.
中科院分区:
化学1区
文献类型:
--
作者:
Allen, Peter M.;Liu, Wenhao;Chauhan, Vikash P.;Lee, Jungmin;Ting, Alice Y.;Fukumura, Dai;Jain, Rakesh K.;Bawendi, Moungi G.

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We present the synthesis of InAs quantum dots (QDs) with a ZnCdS shell with bright and stable emission in the near-infrared (NIR, 700−900 nm) region for biological imaging applications. We demonstrate how NIR QDs can image tumor vasculaturein vivoat significantly deeper penetration depths and with higher contrast than visible emitting CdSe(CdS) QDs. Targeted cellular labeling is also presented and may enable multiplexed and low autofluorescence cellular imaging.
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