Probiotics in the prophylaxis of COVID-19: something is better than nothing.
Probiotics in the prophylaxis of COVID-19: something is better than nothing.
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DOI：
10.1007/s13205-020-02554-1
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发表时间：
2021-01
期刊：
影响因子：
2.8
通讯作者：
Dharne M
中科院分区：
文献类型：
--
作者：
Gohil K;Samson R;Dastager S;Dharne M
新冠肺炎的新一轮病毒大流行是由一种新型冠状病毒(SARS-CoV-2)引起的，它给世界带来了又一次前所未有的卫生和经济危机。由于缺乏特定的治疗方法，有必要采取其他策略来防止由这种以前未知的病毒病原体引起的感染的传播。最近的一些证据表明，新冠肺炎病与肠道生物失调之间存在联系。益生菌包括活的微生物，口服后通过重塑肠道微生物区系的组成而有益于人类健康。胃肠道和呼吸道的密切亲缘关系表明，为什么一个人的功能障碍可能会引发其他人的疾病。新出现的研究表明，益生菌具有调节呼吸系统免疫反应的能力。益生菌对几种呼吸道病毒感染的疗效之前已经进行了研究。因此，该综述旨在了解益生菌在呼吸道病毒感染过程中所介导的肠道-肺免疫的现有信息，以及在新冠肺炎大流行中作为预防措施的给药在处理肠道微生物失调中的作用。
The new viral pandemic of COVID-19 is caused by a novel coronavirus (SARS-CoV-2) that has brought the world at another unprecedented crisis in terms of health and economy. The lack of specific therapeutics necessitates other strategies to prevent the spread of infection caused by this previously unknown viral etiological agent. Recent pieces of evidence have shown an association between COVID-19 disease and intestinal dysbiosis. Probiotics comprise living microbes that upon oral administration benefit human health by reshaping the composition of gut microbiota. The close kinship of the gastrointestinal and respiratory tract suggests why the dysfunction of one may incite illness in others. The emerging studies suggest the capability of probiotics to regulate immune responses in the respiratory system. The efficacy of probiotics has been studied previously on several respiratory tract viral infections. Therefore, the purpose of this review is to comprehend existing information on the gut mediated-pulmonary immunity conferred by probiotic bacteria, in the course of respiratory virus infections and administration as a prophylactic measure in COVID-19 pandemic in managing intestinal dysbiosis as well.
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