RAID v2.0: an updated resource of RNA-associated interactions across organisms.
RAID v2.0: an updated resource of RNA-associated interactions across organisms.
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DOI:
10.1093/nar/gkw1052
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发表时间:
2017-01-04
影响因子:
14.9
通讯作者:
Wang D
中科院分区:
文献类型:
--
作者:
Yi Y;Zhao Y;Li C;Zhang L;Huang H;Li Y;Liu L;Hou P;Cui T;Tan P;Hu Y;Zhang T;Huang Y;Li X;Yu J;Wang D
With the development of biotechnologies and computational prediction algorithms, the number of experimental and computational prediction RNA-associated interactions has grown rapidly in recent years. However, diverse RNA-associated interactions are scattered over a wide variety of resources and organisms, whereas a fully comprehensive view of diverse RNA-associated interactions is still not available for any species. Hence, we have updated the RAID database to version 2.0 (RAID v2.0, www.rna-society.org/raid/) by integrating experimental and computational prediction interactions from manually reading literature and other database resources under one common framework. The new developments in RAID v2.0 include (i) over 850-fold RNA-associated interactions, an enhancement compared to the previous version; (ii) numerous resources integrated with experimental or computational prediction evidence for each RNA-associated interaction; (iii) a reliability assessment for each RNA-associated interaction based on an integrative confidence score; and (iv) an increase of species coverage to 60. Consequently, RAID v2.0 recruits more than 5.27 million RNA-associated interactions, including more than 4 million RNA–RNA interactions and more than 1.2 million RNA–protein interactions, referring to nearly 130 000 RNA/protein symbols across 60 species.
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通讯作者:
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