Familial Aspects of the Type A Behavior Pattern and Physiologic Reactivity to Stress
Familial Aspects of the Type A Behavior Pattern and Physiologic Reactivity to Stress
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A 型行为模式的家庭方面和对压力的生理反应
DOI：
10.1007/978-3-642-71234-0_14
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发表时间：
1986
期刊：
影响因子：
168.9
通讯作者：
C. J. Rakaczky
中科院分区：
文献类型：
--
作者：
K. Matthews;C. J. Rakaczky
家族性因素在冠心病（CHD）的病因和病程中起着重要的作用，这一点越来越清楚。冠心病患者的一级亲属发生冠状动脉事件的风险较高（Slack和Evans 1966）。在Western Collaborative Group Study （WCGS）中，研究开始时年龄在39-49岁之间且有冠心病家族史的男性在81/ 21年的随访期间患冠心病的风险较高（Rosenman et al. 1975）。虽然冠心病家族史发挥其致病作用的机制尚不完全清楚，但它们可能部分归因于出生时冠状动脉的基本形态特征，这为随后的动脉粥样硬化发展提供了基础（见Neufeld和Blieden 1978）。它们也可能是由于冠心病主要危险因素的家族聚集性及其相关的病理生理过程。例如，在各种研究中，有血缘关系的父母和孩子的血压水平在0.28和0.37之间相关，而父母和收养的孩子的血压水平没有显著相关（Feinleib et al. 1980）。至少在成年期，血压的部分家族聚集性似乎是由于另一个危险因素的家族聚集性，即肥胖（例如，Carney et al. 1976）。胆固醇水平和糖尿病似乎也在家族中聚集（例如，Sing et al. 1980）。此外，影响健康的生活方式因素，如饮食偏好、运动习惯和吸烟，显然是人们在早期家庭生活中所处的态度、行为模式和社会环境所导致的行为。
It has become increasingly clear that familial factors play an important role in the etiology and course of coronary heart disease (CHD). First-degree relatives of patients with CHD are at elevated risk for a coronary event (Slack and Evans 1966). In the Western Collaborative Group Study (WCGS), men who were 39–49 years old at study onset and had a family history of CHD were at elevated risk for CHD during the 81/2year follow-up period (Rosenman et al. 1975). Although the mechanisms by which family history of CHD exerts its pathogenic influence are not entirely clear, they are likely to be due in part to basic morphological features of the coronary arteries present at birth, which provide the foundation for subsequent development of atherosclerosis (see Neufeld and Blieden 1978). They are also likely to be due to familial clustering of major risk factors for CHD and their associated pathophysiological processes. For example, blood pressure levels of biologically related parents and children correlate between 0.28 and 0.37 in various studies, whereas the blood pressure levels of parents and adopted children do not correlate significantly (Feinleib et al. 1980). Part of the familial clustering of blood pressure, at least in adulthood, appears to be due to the familial clustering of another risk factor, obesity (e.g., Carney et al. 1976). Cholesterol levels and diabetes also appear to aggregate in the family (e.g., Sing et al. 1980). Furthermore, life-style factors that influence health, such as diet preferences, exercise habits, and smoking, are clearly behaviors that result from the attitudes, role models, and social milieu to which persons are exposed in early family life.
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父母高血压和心血管对认知和等长挑战的反应。
影响因子：
3.7
作者：
Manuck,SB;Proietti,JM
通讯作者：
Proietti,JM
心理压力会导致高血压高危男性的钠和液体潴留。
DOI：
10.1126/science.6836285
发表时间：
1983
期刊：
Science (New York, N.Y.)
影响因子：
--
作者：
Light,KC;Koepke,JP;Obrist,PA;Willis4th,PW
通讯作者：
Willis4th,PW
与高血压相关的生理生化因素的童年家族和种族差异。
DOI：
10.1161/01.hyp.5.1.56
发表时间：
1983
期刊：
Hypertension (Dallas, Tex. : 1979)
影响因子：
--
作者：
Hohn,AR;Riopel,DA;Keil,JE;Loadholt,CB;Margolius,HS;Halushka,PV;Privitera,PJ;Webb,JG;Medley,ES;Schuman,SH;Rubin,MI;Pantell,RH;Braunstein,ML
通讯作者：
Braunstein,ML
影响因子：
22.4
作者：
KRANTZ, DS;MANUCK, SB
通讯作者：
MANUCK, SB
健康年轻人父母高血压和心血管对压力的反应。
影响因子：
3.7
作者：
Hastrup,JL;Light,KC;Obrist,PA
通讯作者：
Obrist,PA