A Review of Diterpenes from Marine-Derived Fungi: 2009-2021.

A Review of Diterpenes from Marine-Derived Fungi: 2009-2021.
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海洋来源真菌中二萜的综述:2009 年至 2021 年

DOI:
10.3390/molecules27238303
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发表时间:
2022-11-28
期刊:
影响因子:
4.6
通讯作者:
Shao, Zongze
Shao, Zongze
中科院分区:
化学2区
文献类型:
--
作者:
Qiu, Peng;Xia, Jinmei;Zhang, Haitao;Lin, Donghai;Shao, Zongze

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海洋真菌是新化合物和生物活性代谢产物的重要来源。二萜类化合物是一类重要的天然产物,具有抗病毒、抗菌、抗炎、抗疟、细胞毒等多种生物活性。随着深海样品采集设备的发展,发现了更多的海洋真菌,其多样性也在不断增加,在过去十年中,从海洋真菌中鉴定具有新结构和生物活性的二萜类化合物方面取得了很大进展。本文综述了2009 - 2021年从海洋真菌中分离得到的237种二萜类化合物的化学结构、产生菌和生物活性。本文对海洋真菌作为生物活性二萜类化合物来源的研究进展进行了综述。
Marine-derived fungi are important sources of novel compounds and pharmacologically active metabolites. As an important class of natural products, diterpenes show various biological activities, such as antiviral, antibacterial, anti-inflammatory, antimalarial, and cytotoxic activities. Developments of equipment for the deep-sea sample collection allow discoveries of more marine-derived fungi with increasing diversity, and much progress has been made in the identification of diterpenes with novel structures and bioactivities from marine fungi in the past decade. The present review article summarized the chemical structures, producing organisms and biological activities of 237 diterpenes which were isolated from various marine-derived fungi over the period from 2009 to 2021. This review is beneficial for the exploration of marine-derived fungi as promising sources of bioactive diterpenes.
来自红树林内生真菌不规则毛霉 QEN-189 的根变体 A-F、吲哚二萜
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