The relationship of body mass index and waist-hip ratio on the 9-year incidence of diabetes and hypertension in a predominantly African-origin population.

The relationship of body mass index and waist-hip ratio on the 9-year incidence of diabetes and hypertension in a predominantly African-origin population.
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DOI:
10.1016/j.annepidem.2008.02.006
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发表时间:
2008-08
影响因子:
5.6
通讯作者:
Leske, M. Cristina
Leske, M. Cristina
中科院分区:
医学3区
文献类型:
--
作者:
Nemesure, Barbara;Wu, Suh-Yuh;Hennis, Anselm;Leske, M. Cristina

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在非洲裔加勒比人群中,提供2型糖尿病和高血压的9年发病率数据,并评价体重指数(BMI)和腰臀比(WHR)与这些合并症的关系。一项纵向的、基于人群的队列研究,包括基线时的4,631名参与者; 2,793名参与者在9年随访时重新检查。2型糖尿病定义为自我报告病史和/或GHb测量;高血压定义为收缩压(BP)≥140 mmHg和/或舒张压≥90 mmHg和/或使用抗高血压治疗。发病率基于基线时无此类疾病的人群。女性9年高血压发病率(95%置信区间)[37.5%(34.0,41.2)]高于男性[30.6%(26.9,34.6)],而两种性别的糖尿病发病率相似(14%)。体型与这两种情况有关;然而,高血压的发病率与WHR的相关性更强,而糖尿病与BMI的相关性更强。糖尿病和高血压的发病率在这个队列中很高,BMI和WHR与这些合并症的关系是显著的。这些研究结果表明,需要制定针对性的干预措施和预防战略,在这个非洲-加勒比和类似的高风险人群。
To provide 9-year incidence data for type 2 diabetes and hypertension and evaluate the relationship of body mass index (BMI) and waist-hip ratio (WHR) on these comorbidities in an Afro-Caribbean population. A longitudinal, population-based cohort study including 4,631 participants at baseline; 2,793 were reexamined at the 9-year follow-up. Type 2 diabetes was defined by self-reported history and/or GHb measurement; hypertension was defined as systolic blood pressure (BP) ≥140 mmHg and/or diastolic BP ≥90 mmHg and/or use of antihypertensive treatment. Incidence rates were based on persons without such conditions at baseline. The 9-year incidence of hypertension (95% confidence interval) was higher in women [37.5% (34.0, 41.2)] than men [30.6% (26.9, 34.6)], whereas the incidence of diabetes was similar for both genders (14%). Body size was related to both conditions; however, the incidence of hypertension was more strongly associated to WHR, whereas diabetes had a stronger association with BMI. Incidence rates for diabetes and hypertension were high in this cohort and the relationship of BMI and WHR on these co-morbidities was significant. These findings suggest the need to develop tailored interventions and preventive strategies in this Afro-Caribbean and similar high risk populations.
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