Do hydrogen peroxide mouthwashes have a virucidal effect? A systematic review.
Do hydrogen peroxide mouthwashes have a virucidal effect? A systematic review.
复制标题
DOI：
10.1016/j.jhin.2020.10.003
复制
发表时间：
2020-12
期刊：
影响因子：
--
通讯作者：
Braz-Silva PH
中科院分区：
文献类型：
--
作者：
Ortega KL;Rech BO;El Haje GLC;Gallo CB;Pérez-Sayáns M;Braz-Silva PH
唾液中存在严重急性呼吸综合征冠状病毒2(SARS-CoV-2)，提醒卫生专业人员注意在一些程序中产生的气雾剂污染的可能性。含有1%过氧化氢的口腔手术前含1%双氧水用于降低口腔手术前唾液中SARS-CoV-2病毒载量的手术前含漱液的适应症通过几次引用得到了显著传播，并影响了在此次大流行期间制定牙科护理方案的各种牙科协会，包括住进医院病房和重症监护病房的患者。我们的目的是进行一项系统的审查，以回答以下问题：过氧化氢(任何浓度)含漱液是否具有杀灭病毒的效果？检索Cochrane、Lilacs、PubMed、Scope us和Embase数据库，检索词为“过氧化氢”、“漱口水”、“口腔漱口水”、“沐浴”、“洗口水”和“漱口水”。综述、致编辑的信、个人意见、书籍章节、案例报告、国会摘要、动物研究以及含过氧化氢以外其他化合物的漱口水研究被排除在外。在最初的搜索中，在五个电子数据库上找到了1342篇文章。剔除部分重复项后，剩下976篇文章。无论发表日期如何，只选择了评估过氧化氢漱口水杀灭病毒效果的研究。在阅读标题和摘要后，没有一篇文章符合资格标准。总而言之，没有科学证据表明双氧水可以控制唾液中SARS-CoV-2或任何其他病毒的病毒载量。
The presence of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in saliva has alerted health professionals to the possibility of contamination by aerosols generated in a number of procedures. The indication of preoperative mouthwash containing 1% hydrogen peroxide for reducing the viral load of SARS-CoV-2 in saliva prior to oral procedures has been significantly disseminated through several citations and influenced various dental associations in the elaboration of dental care protocols during this pandemic period, including patients admitted to hospital wards and intensive care units. To Our aim was to perform a systematic review to answer the following question: does hydrogen peroxide mouthwash (at any concentration) have a virucidal effect? The Cochrane, LILACS, PubMed, Scopus, and Embase databases were searched by using the following key-words: ‘hydrogen peroxide’, ‘mouthwash’, ‘mouth rinse’, ‘rinse’, ‘oral rinse’, ‘mouth bath’, ‘mouth wash’, and ‘mouth washes’. Reviews, letters to the editor, personal opinions, book chapters, case reports, congress abstracts, studies with animals and studies on mouthwash containing other compounds other than hydrogen peroxide were excluded. During the initial search 1342 articles were identified on the five electronic databases. After excluding some duplicates, 976 articles remained. Only studies assessing the virucidal effect of hydrogen peroxide mouthwash were selected, regardless of publication date. After reading titles and abstracts, no article met the eligibility criteria. In conclusion, there is no scientific evidence supporting the indication of hydrogen peroxide mouthwash for control of the viral load regarding SARS-CoV-2 or any other viruses in saliva.
登录
查看更多内容
DOI：
10.1016/j.oooo.2012.11.019
发表时间：
2013-06-01
影响因子：
2.9
作者：
DuVall, Nicholas B.;Fisher, Tommy D.;Vandewalle, Kraig S.
通讯作者：
Vandewalle, Kraig S.
影响因子：
7.3
作者：
Hamming, I;Timens, W;van Goor, H
通讯作者：
van Goor, H
DOI：
10.1590/1678-7757-2017-0112
发表时间：
2017-11
期刊：
Journal of applied oral science : revista FOB
影响因子：
--
作者：
Balejo RDP;Cortelli JR;Costa FO;Cyrino RM;Aquino DR;Cogo-Müller K;Miranda TB;Moura SP;Cortelli SC
通讯作者：
Cortelli SC
DOI：
10.1016/s1079-2104(05)80124-6
发表时间：
1995-04-01
影响因子：
--
作者：
DENNISON, DK;MEREDITH, GM;CAFFESSE, RG
通讯作者：
CAFFESSE, RG
影响因子：
4.7
作者：
Badran Z;Gaudin A;Struillou X;Amador G;Soueidan A
通讯作者：
Soueidan A