Periodontal pockets: A potential reservoir for SARS-CoV-2?

Periodontal pockets: A potential reservoir for SARS-CoV-2?
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DOI:
10.1016/j.mehy.2020.109907
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发表时间:
2020-10
期刊:
影响因子:
4.7
通讯作者:
Soueidan A
Soueidan A
中科院分区:
医学4区
文献类型:
--
作者:
Badran Z;Gaudin A;Struillou X;Amador G;Soueidan A

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牙周袋是牙周炎的主要临床表现,牙周炎是一种影响牙齿支持组织的慢性炎症性口腔疾病,在成年人群中患病率很高。牙周袋是龈下细菌生物膜的理想环境,其与龈上口腔、牙周袋的粘膜组织和外周循环系统相互作用。牙周袋已被发现窝藏病毒物种,如单纯疱疹病毒的家庭。最近,SARS-CoV-2引起了科学界/医学界的极大兴趣,因为它导致了全球大流行(Covid-19),并使地球仪瘫痪,全球感染人数众多。这种病毒的行为仍然是部分理解,通过分析它的一些功能,我们假设牙周袋可能是一个有利的解剖生态位的病毒,从而作为一个水库SARS-CoV-2。
Periodontal pockets are the major clinical manifestation of Periodontitis, a chronic inflammatory oral disease affecting the teeth-supporting tissues and has high prevalence in the adult population. Periodontal pockets are ideal environments for subgingival bacterial biofilms, that interact with the supragingival oral cavity, mucosal tissues of the pocket and a peripheral circulatory system. Periodontal pockets have been found to harbor viral species such as the Herpes simplex viruses’ family. Recently, the SARS-CoV-2 has gained major interest of the scientific/medical community as it caused a global pandemic (Covid-19) and paralyzed the globe with high figures of infected people worldwide. This virus behavior is still partially understood, and by analyzing some of its features we hypothesized that periodontal pocket could be a favorable anatomical niche for the virus and thus acting as a reservoir for SARS-CoV-2.
慢性和侵袭性牙周炎不同探诊深度的牙周袋龈下微生物组:一项初步研究
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