MetaboLights--an open-access general-purpose repository for metabolomics studies and associated meta-data.
MetaboLights--an open-access general-purpose repository for metabolomics studies and associated meta-data.
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DOI：
10.1093/nar/gks1004
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发表时间：
2013-01
影响因子：
14.9
通讯作者：
Steinbeck C
中科院分区：
文献类型：
--
作者：
Haug K;Salek RM;Conesa P;Hastings J;de Matos P;Rijnbeek M;Mahendraker T;Williams M;Neumann S;Rocca-Serra P;Maguire E;González-Beltrán A;Sansone SA;Griffin JL;Steinbeck C
Http://www.ebi.ac.uk/metabolights)是第一个用于代谢组学研究及其原始实验数据和相关元数据的通用、开放获取的存储库，由分子生物学领域的主要开放获取数据提供商之一维护。代谢组谱是研究生物功能和疾病、饮食和环境引起的系统扰动的重要工具。这些方法的有效性取决于在广泛的实验方法和条件下公开开放数据的可用性。由开源ISA框架提供支持的MetabLights存储库是跨物种和跨技术的。它将涵盖代谢物结构及其参考光谱，以及它们的生物学作用、位置、浓度和代谢实验的原始数据。研究自动收到一个稳定的唯一登录号，可用作出版参考(例如MTBLS1)。目前，该资料库包括15项提交的研究，涵盖714种分析的93项方案，涵盖8个不同物种，包括人、秀丽线虫、小鼠和拟南芥。在这些研究中发现的代谢物中，有827被映射到Chebi。这些研究涵盖了各种技术，包括核磁共振光谱和质谱学。
MetaboLights (http://www.ebi.ac.uk/metabolights) is the first general-purpose, open-access repository for metabolomics studies, their raw experimental data and associated metadata, maintained by one of the major open-access data providers in molecular biology. Metabolomic profiling is an important tool for research into biological functioning and into the systemic perturbations caused by diseases, diet and the environment. The effectiveness of such methods depends on the availability of public open data across a broad range of experimental methods and conditions. The MetaboLights repository, powered by the open source ISA framework, is cross-species and cross-technique. It will cover metabolite structures and their reference spectra as well as their biological roles, locations, concentrations and raw data from metabolic experiments. Studies automatically receive a stable unique accession number that can be used as a publication reference (e.g. MTBLS1). At present, the repository includes 15 submitted studies, encompassing 93 protocols for 714 assays, and span over 8 different species including human, Caenorhabditis elegans, Mus musculus and Arabidopsis thaliana. Eight hundred twenty-seven of the metabolites identified in these studies have been mapped to ChEBI. These studies cover a variety of techniques, including NMR spectroscopy and mass spectrometry.
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HMDB：人类代谢组数据库。
影响因子：
14.9
作者：
Wishart, David S;Tzur, Dan;Knox, Craig;Eisner, Roman;Guo, An Chi;Young, Nelson;Cheng, Dean;Jewell, Kevin;Arndt, David;Sawhney, Summit;Fung, Chris;Nikolai, Lisa;Lewis, Mike;Coutouly, Marie-Aude;Forsythe, Ian;Tang, Peter;Shrivastava, Savita;Jeroncic, Kevin;Stothard, Paul;Amegbey, Godwin;Block, David;Hau, David D;Wagner, James;Miniaci, Jessica;Clements, Melisa;Gebremedhin, Mulu;Guo, Natalie;Zhang, Ying;Duggan, Gavin E;Macinnis, Glen D;Weljie, Alim M;Dowlatabadi, Reza;Bamforth, Fiona;Clive, Derrick;Greiner, Russ;Li, Liang;Marrie, Tom;Sykes, Brian D;Vogel, Hans J;Querengesser, Lori
通讯作者：
Querengesser, Lori
影响因子：
3.6
作者：
Goodacre, Royston;Broadhurst, David;Wulfert, Florian
通讯作者：
Wulfert, Florian
影响因子：
6.8
作者：
Veldhoen, Nik;Ikonomou, Michael G.;Helbing, Caren C.
通讯作者：
Helbing, Caren C.
DOI：
10.1093/bioinformatics/btq415
发表时间：
2010-09-15
期刊：
Bioinformatics (Oxford, England)
影响因子：
--
作者：
Rocca-Serra P;Brandizi M;Maguire E;Sklyar N;Taylor C;Begley K;Field D;Harris S;Hide W;Hofmann O;Neumann S;Sterk P;Tong W;Sansone SA
通讯作者：
Sansone SA
影响因子：
14.9
作者：
Ulrich EL;Akutsu H;Doreleijers JF;Harano Y;Ioannidis YE;Lin J;Livny M;Mading S;Maziuk D;Miller Z;Nakatani E;Schulte CF;Tolmie DE;Kent Wenger R;Yao H;Markley JL
通讯作者：
Markley JL