Metabolic syndrome among Sri Lankan adults: prevalence, patterns and correlates.
Metabolic syndrome among Sri Lankan adults: prevalence, patterns and correlates.
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DOI：
10.1186/1758-5996-4-24
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发表时间：
2012-05-31
影响因子：
4.8
通讯作者：
Matthews DR
中科院分区：
文献类型：
--
作者：
Katulanda P;Ranasinghe P;Jayawardana R;Sheriff R;Matthews DR
代谢综合征（MS）会增加患冠状动脉疾病、中风和糖尿病的风险。在美国的南亚移民中，多发性硬化症的发病率是本土白种人的两倍。在南亚国家，没有关于多发性硬化症患病率的具有全国代表性的研究。本研究旨在评估斯里兰卡成年人中多发性硬化症的患病率，并调查其与社会人口统计学、临床和生化参数的关系。关于多发性硬化症及其相关细节的数据来自于2005-2006年间进行的一项基于人群的横断面研究。MS是根据国际糖尿病联合会的标准定义的。使用二分变量MS（0 =缺席，1 =存在）进行二元逻辑回归分析。独立协变量为：性别、年龄类别、居住地区、种族、教育水平、收入和体育活动。样本量为4485例（有效率89.7%），其中男性39.5%，平均年龄46.1±15.1岁。MS的粗患病率为27.1% (95% CI: 25.8-28.5)，年龄校正患病率为24.3% （95% CI: 23.0-25.6）。男性和女性患病率分别为18.4% （95% CI: 16.5-20.3）和28.3% (95% CI: 26.6-30.0) （p < 0.001）。城市成年人（34.8% [95% CI: 31.8-37.9]）的患病率明显高于农村成年人（21.6% [95% CI: 20.2-23.0]）。在种族群体中，斯里兰卡摩尔人的MS患病率最高（43.0% [95% CI: 37.2-48.9]）。在所有成年人中，教育水平和家庭月收入最高的人都有多发性硬化症。在IPAQ的不同体育活动类别中，多发性硬化症的患病率为；“不活跃”-38.8% (95% CI 34.5-43.2)，“适度活跃”-33.5% （95% CI 30.9-36.1）和“活跃”-21.1% （95% CI 19.6-22.7）。二元logistic回归分析结果表明，女性性别（OR:1.7）、年龄增长、城市生活（OR:1.7）、摩尔民族（OR:2.6）、中等教育（OR:1.5）和高等教育水平（OR:2.3）、家庭月收入LKR 7,000-24,999 （OR:1.5）和bbb50,000 （OR:2.1）以及缺乏运动（OR:1.6）都显著增加了斯里兰卡成年人患MS的风险，影响了近四分之一的人口。女性、年龄增长、城市生活、较高的社会经济地位和缺乏体育锻炼是重要的相关因素。
Metabolic Syndrome (MS) increases the risk for Coronary Artery Disease, stroke and diabetes. MS is twice more common amongst South Asian immigrants in US compared to native Caucasians. There are no nationally representative studies on prevalence of MS from any of the South Asian countries. The present study aims to evaluate the prevalence of MS among Sri Lankan adults and investigates its relationships with socio-demographic, clinical and biochemical parameters. Data on MS and its associated details were obtained from a population-based cross-sectional study conducted between years 2005–2006. MS was defined according to the International Diabetes Federation criteria. A binary logistic regression analysis was performed using the dichotomous variable MS (0 = absent, 1 = present). The independent co-variants were: gender, age category, area of residence, ethnicity, level of education, income and physical activity. Sample size was 4,485 (Response rate–89.7%), 39.5% were males and mean age was 46.1 ± 15.1 years. The crude prevalence of MS was 27.1% (95% CI: 25.8–28.5), and age-adjusted prevalence was 24.3% (95% CI: 23.0–25.6). Prevalence in males and females were 18.4% (95% CI: 16.5–20.3) and 28.3% (95% CI: 26.6–30.0) respectively (p < 0.001). Urban adults (34.8% [95% CI: 31.8–37.9]) had a significantly higher prevalence than rural adults (21.6% [95% CI: 20.2–23.0]). Among ethnic groups, the highest prevalence of MS was observed in Sri Lankan Moors (43.0% [95% CI: 37.2–48.9]). In all adults, MS was observed in those with the highest level of education and monthly household income. Prevalence of MS in the different physical activity categories of the IPAQ were; ‘inactive’–38.8% (95% CI 34.5-43.2), ‘moderately active’–33.5% (95% CI 30.9-36.1) and ‘active’–21.1% (95% CI 19.6-22.7). The results of the binary logistic regression analysis indicates that female gender (OR:1.7), increasing age, urban living (OR:1.7), Moor ethnicity (OR:2.6), secondary (OR:1.5) and tertiary levels of education (OR:2.3), monthly household income LKR 7,000–24,999 (OR:1.5) and >50,000 (OR:2.1), and physical inactivity (OR:1.6), all significantly increased risk of developing MS. MS is common among Sri Lankan adults affecting nearly one-fourth of the population. Female gender, increasing age, urban living, higher socio-economical status and physical inactivity were important associated factors.
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影响因子：
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