Psychiatric implications of basic and clinical studies with corticotropin-releasing factor.
Psychiatric implications of basic and clinical studies with corticotropin-releasing factor.
复制标题
促肾上腺皮质激素释放因子的基础和临床研究的精神病学意义。
DOI:
10.1176/ajp.141.5.619
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发表时间:
1984
期刊:
影响因子:
--
通讯作者:
D. Loriaux
中科院分区:
文献类型:
--
作者:
P. Gold;G. Chrousos;C. Kellner;R. Post;A. Roy;P. Augerinos;Heinrich M. Schulte;E. Oldfield;D. Loriaux
Corticotropin-releasing factor (CRF) is a newly sequenced neuropeptide thought to be a principal stimulus to pituitary corticotropin (ACTH) secretion. Evidence obtained from laboratory animals and primates is reviewed which indicates that CRF not only stimulates the pituitary-adrenal axis but also influences several aspects of CNS function which may be of relevance to psychiatric illness. Clinically, experience in administering ovine CRF to more than 150 individuals shows that CRF can be helpful in resolving differential diagnostic dilemmas in patients with various disorders of the hypothalamic-pituitary-adrenal axis and in furthering an understanding of the pathophysiology of conditions such as Cushing's disease and depression.
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DOI:
10.1126/science.7268432
发表时间:
1981
期刊:
Science (New York, N.Y.)
影响因子:
--
作者:
Reppert,SM;Artman,HG;Swaminathan,S;Fisher,DA
通讯作者:
Fisher,DA
影响因子:
56.9
作者:
ALDENHOFF, JB;GRUOL, DL;SIGGINS, GR
通讯作者:
SIGGINS, GR
影响因子:
4.8
作者:
Rivier,C;Vale,W
通讯作者:
Vale,W
影响因子:
4.8
作者:
RIVIER, C;VALE, W
通讯作者:
VALE, W