Behavioral interventions for reducing head motion during MRI scans in children.
Behavioral interventions for reducing head motion during MRI scans in children.
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DOI：
10.1016/j.neuroimage.2018.01.023
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发表时间：
2018-05-01
期刊：
影响因子：
5.7
通讯作者：
Dosenbach NUF
中科院分区：
文献类型：
--
作者：
Greene DJ;Koller JM;Hampton JM;Wesevich V;Van AN;Nguyen AL;Hoyt CR;McIntyre L;Earl EA;Klein RL;Shimony JS;Petersen SE;Schlaggar BL;Fair DA;Dosenbach NUF
A major limitation to structural and functional MRI (fMRI) scans is their susceptibility to head motion artifacts. Even submillimeter movements can systematically distort functional connectivity, morphometric, and diffusion imaging results. In patient care, sedation is often used to minimize head motion, but it incurs increased costs and risks. In research settings, sedation is typically not an ethical option. Therefore, safe methods that reduce head motion are critical for improving MRI quality, especially in high movement individuals such as children and neuropsychiatric patients. We investigated the effects of (1) viewing movies and (2) receiving real-time visual feedback about head movement in 24 children (5–15 years old). Children completed fMRI scans during which they viewed a fixation cross (i.e., rest) or a cartoon movie clip, and during some of the scans they also received real-time visual feedback about head motion. Head motion was significantly reduced during movie watching compared to rest and when receiving feedback compared to receiving no feedback. However, these results depended on age, such that the effects were largely driven by the younger children. Children older than 10 years showed no significant benefit. We also found that viewing movies significantly altered the functional connectivity of fMRI data, suggesting that fMRI scans during movies cannot be equated to standard resting-state fMRI scans. The implications of these results are twofold: (1) given the reduction in head motion with behavioral interventions, these methods should be tried first for all clinical and structural MRIs in lieu of sedation; and (2) for fMRI research scans, these methods can reduce head motion in certain groups, but investigators must keep in mind the effects on functional MRI data.
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影响因子：
4.7
作者：
Greene DJ;Black KJ;Schlaggar BL
通讯作者：
Schlaggar BL
影响因子：
3
作者：
Hagmann P;Grant PE;Fair DA
通讯作者：
Fair DA
影响因子：
11
作者：
Greene DJ;Williams Iii AC;Koller JM;Schlaggar BL;Black KJ;The Tourette Association of America Neuroimaging Consortium
通讯作者：
The Tourette Association of America Neuroimaging Consortium
影响因子：
5.7
作者：
Dosenbach NUF;Koller JM;Earl EA;Miranda-Dominguez O;Klein RL;Van AN;Snyder AZ;Nagel BJ;Nigg JT;Nguyen AL;Wesevich V;Greene DJ;Fair DA
通讯作者：
Fair DA
影响因子：
2.9
作者：
Hess, Aaron T.;Andronesi, Ovidiu C.;Meintjes, Ernesta M.
通讯作者：
Meintjes, Ernesta M.