Influence of Hydroxyapatite Nanoparticles and Surface Plasma Treatment on Bioactivity of Polycaprolactone Nanofibers.
Influence of Hydroxyapatite Nanoparticles and Surface Plasma Treatment on Bioactivity of Polycaprolactone Nanofibers.
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DOI：
10.3390/polym12091877
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发表时间：
2020-08-20
期刊：
影响因子：
5
通讯作者：
Rahel J
中科院分区：
文献类型：
--
作者：
Stastna E;Castkova K;Rahel J
众所周知，纳米纤维是一种有益的组织工程结构。由于天然聚合物的高获取成本和它们的环境问题处理（有毒溶解剂），人造聚合物似乎是医疗用途的更好选择。本研究采用静电纺丝法制备了聚己内酯纳米纤维结构。测试了材料形态（无规或定向纤维对连续层）和一部分羟基磷灰石纳米颗粒的存在对细胞增殖的影响。此外，还评价了低温氩放电等离子体处理改善材料润湿性的效果。我们已经表明，羟基磷灰石颗粒以及等离子体表面处理是有益的细胞增殖。这两种影响的显著影响在测试的前48小时内是明显的：与对照相比，聚己内酯纤维中的羟基磷灰石颗粒加速了10%的增殖，而等离子体处理的颗粒增强了30%的增殖。
Nanofibers are well known as a beneficial type of structure for tissue engineering. As a result of the high acquisition cost of the natural polymers and their environmentally problematic treatment (toxic dissolution agents), artificial polymers seem to be the better choice for medical use. In the present study, polycaprolactone nano-sized fibrous structures were prepared by the electrospinning method. The impact of material morphology (random or parallelly oriented fibers versus continuous layer) and the presence of a fraction of hydroxyapatite nanoparticles on cell proliferation was tested. In addition, the effect of improving the material wettability by a low temperature argon discharge plasma treatment was evaluated, too. We have shown that both hydroxyapatite particles as well as plasma surface treatment are beneficial for the cell proliferation. The significant impact of both influences was evident during the first 48 h of the test: the hydroxyapatite particles in polycaprolactone fibers accelerated the proliferation by 10% compared to the control, and the plasma-treated ones enhanced proliferation by 30%.
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DOI：
10.1016/j.msec.2006.05.019
发表时间：
2007-04-01
期刊：
MATERIALS SCIENCE & ENGINEERING C-BIOMIMETIC AND SUPRAMOLECULAR SYSTEMS
影响因子：
--
作者：
Lannutti, J.;Reneker, D.;Farson, D. F.
通讯作者：
Farson, D. F.
影响因子：
2.9
作者：
Kitamura, E;Stegaroiu, R;Miyakawa, O
通讯作者：
Miyakawa, O
影响因子：
6
作者：
Can-Herrera, L. A.;Avila-Ortega, A.;Cervantes-Uc, J. M.
通讯作者：
Cervantes-Uc, J. M.
影响因子：
6.1
作者：
Bhatia, Sujata K.;Yetter, Ann B.
通讯作者：
Yetter, Ann B.
DOI：
10.1016/s0927-7757(97)00133-7
发表时间：
1998-02-15
影响因子：
5.2
作者：
Bergstrom, L
通讯作者：
Bergstrom, L